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pubmed-article:3180544pubmed:abstractTextA clinical, radiological and immunogenetical study was carried out on 51 Crohn's patients. Rheumatological disorders were found in 16 of them, with higher frequency in those with colon involvement only. A statistically significant increase in the frequencies of HLA-A9 and HLA-Cw3 was noted: Cw3 showed a particularly high frequency in males, and A9 in younger patients. The frequency of HLA-B27 was significantly increased in the patients with colon involvement. In the group of 16 patients with rheumatic diseases HLA antigen frequencies were not significantly different from the control population.lld:pubmed
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pubmed-article:3180544pubmed:articleTitleHLA antigens and clinical manifestations in Crohn's disease.lld:pubmed
pubmed-article:3180544pubmed:affiliationDivisione di Reumatologia, Ospedale S. Giovanni, Torino, Italy.lld:pubmed
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