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pubmed-article:3177466pubmed:abstractTextAn analysis of the linkage of a non-syndromal form of X-linked mental retardation (MRX1) with a number of markers on the X chromosome was performed in a large pedigree. The affected males had moderate mental retardation; in all other clinical respects and cytogenetically they were normal. No recombinants were observed between the MRX1 gene and the marker DXS14 (p58.1) located at Xp11-cen (Z (max.) = 2.12 at theta = 0.00). Recombination was observed between the MRX1 gene and the markers DXS7 and DXYS1 which flank DXS14. This form of XLMR maps to the centromeric portion of the X-chromosome.lld:pubmed
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pubmed-article:3177466pubmed:articleTitleA non-syndromal form of X-linked mental retardation (XLMR) is linked to DXS14.lld:pubmed
pubmed-article:3177466pubmed:affiliationDepartment of Histopathology, Adelaide Children's Hospital, South Australia.lld:pubmed
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