pubmed-article:3158700 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:3158700 | lifeskim:mentions | umls-concept:C0332307 | lld:lifeskim |
pubmed-article:3158700 | lifeskim:mentions | umls-concept:C0004561 | lld:lifeskim |
pubmed-article:3158700 | lifeskim:mentions | umls-concept:C0039194 | lld:lifeskim |
pubmed-article:3158700 | lifeskim:mentions | umls-concept:C0020204 | lld:lifeskim |
pubmed-article:3158700 | lifeskim:mentions | umls-concept:C0449450 | lld:lifeskim |
pubmed-article:3158700 | lifeskim:mentions | umls-concept:C0002131 | lld:lifeskim |
pubmed-article:3158700 | pubmed:issue | 1 | lld:pubmed |
pubmed-article:3158700 | pubmed:dateCreated | 1985-7-24 | lld:pubmed |
pubmed-article:3158700 | pubmed:abstractText | T cell-depleted, Sephadex G-10-passed unstimulated splenic B cells from C57BL/6 mice stimulated splenic T cells from CKB mice to produce IL 2 and to proliferate. The stimulatory ability of the unstimulated B cells was eliminated by 4000 rad irradiation of the unstimulated stimulator B cells. LPS-activated B cells could stimulate responder T cells more efficiently than unstimulated B cells. For further analysis of allostimulation by B cells, we established a series of alloreactive T cell hybridomas. Forty-five percent of these alloreactive T cell hybridomas could be stimulated to produce IL 2 by either macrophage-dendritic cells or unstimulated B cells. Fifty-five percent of these alloreactive T cell hybridomas could be stimulated by macrophage-dendritic cells but not by unstimulated B cells. T cell hybridomas that were not reactive with unstimulated B cells were also nonreactive to LPS-activated B cells. Analysis of two representative I-Ab-reactive T cell hybridoma clones, B cell-reactive clone CB-11.4 and B cell-nonreactive clone HTB-9.3, revealed again that the stimulatory ability of unstimulated B cells was sensitive to 4000 rad irradiation in the activation of CB-11.4 clone and that CB-11.4 could be stimulated more efficiently by LPS-activated B cells than by unstimulated B cells, but HTB-9.3 could not be stimulated by LPS-activated B cells. Thus, there may be two distinct types of T cells in the alloreaction: B-cell-reactive and B cell-nonreactive. | lld:pubmed |
pubmed-article:3158700 | pubmed:language | eng | lld:pubmed |
pubmed-article:3158700 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3158700 | pubmed:citationSubset | AIM | lld:pubmed |
pubmed-article:3158700 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3158700 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:3158700 | pubmed:month | Jul | lld:pubmed |
pubmed-article:3158700 | pubmed:issn | 0022-1767 | lld:pubmed |
pubmed-article:3158700 | pubmed:author | pubmed-author:KawasakiHH | lld:pubmed |
pubmed-article:3158700 | pubmed:author | pubmed-author:TairaSS | lld:pubmed |
pubmed-article:3158700 | pubmed:author | pubmed-author:MinamiMM | lld:pubmed |
pubmed-article:3158700 | pubmed:author | pubmed-author:NariuchiHH | lld:pubmed |
pubmed-article:3158700 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:3158700 | pubmed:volume | 135 | lld:pubmed |
pubmed-article:3158700 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:3158700 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:3158700 | pubmed:pagination | 111-6 | lld:pubmed |
pubmed-article:3158700 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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pubmed-article:3158700 | pubmed:year | 1985 | lld:pubmed |
pubmed-article:3158700 | pubmed:articleTitle | Alloantigen presentation by B cells: two types of alloreactive T cell hybridomas, B cell-reactive and B cell-nonreactive. | lld:pubmed |
pubmed-article:3158700 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:3158700 | pubmed:publicationType | Comparative Study | lld:pubmed |
pubmed-article:3158700 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3158700 | lld:pubmed |