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pubmed-article:3158389pubmed:abstractTextNon-neoplastic T51B rat liver epithelial cells cannot proliferate in Ca2+-deficient medium. This proliferative inhibition in Ca2+-deficient medium is accompanied by a large reduction in the amount of cellular EDTA-extractable Ca2+/phospholipid-dependent protein kinase (protein kinase C) activity. By contrast, tumorigenic epithelial cells from several Morris hepatomas proliferate in Ca2+-deficient medium and either maintain or greatly increase their content of EDTA-extractable protein kinase C.lld:pubmed
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pubmed-article:3158389pubmed:articleTitleThe influence of extracellular calcium on the distribution of protein kinase C in non-neoplastic and neoplastic rat liver cells.lld:pubmed
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