The nitroreductase enzyme in Walker cells that activates 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB 1954) to 5-(aziridin-1-yl)-4-hydroxylamino-2-nitrobenzamide is a form of NAD(P)H dehydrogenase (quinone) (EC 1.6.99.2).

Source:http://linkedlifedata.com/resource/pubmed/id/3144286

Biochem. Pharmacol. 1988 Dec 15 37 24 4671-7

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3144286