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pubmed-article:3138577pubmed:abstractTextThe effects of 6-hydroxydopamine lesions of the ventral noradrenergic bundle (VNAB) and of intracerebroventricular 6-hydroxydopamine on hypothalamo-hypophyseal portal blood (HPB) concentrations of arginine vasopressin (AVP), corticotrophin releasing factor (CRF-41), and noradrenaline have been investigated. VNAB lesions and intracerebroventricular 6-hydroxydopamine caused a reduction of HPB CRF-41 concentration, while AVP remained unchanged. HPB noradrenaline concentration was reduced in animals treated with lateral ventricular 6-hydroxydopamine, but was unchanged in VNAB lesioned animals. Our results suggest differential effects of noradrenaline on the release of AVP and CRF-41 into HPB.lld:pubmed
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pubmed-article:3138577pubmed:articleTitleDifferential effects of hypothalamic catecholamine depletion on the release of arginine vasopressin and CRF-41 into hypothalamo-hypophyseal portal blood.lld:pubmed
pubmed-article:3138577pubmed:affiliationMedical Unit, Charing Cross and Westminster Medical School, Westminster Hospital, London, U.K.lld:pubmed
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pubmed-article:3138577pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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