| pubmed-article:3134945 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3134945 | lifeskim:mentions | umls-concept:C0027950 | lld:lifeskim |
| pubmed-article:3134945 | lifeskim:mentions | umls-concept:C0919262 | lld:lifeskim |
| pubmed-article:3134945 | lifeskim:mentions | umls-concept:C0043442 | lld:lifeskim |
| pubmed-article:3134945 | lifeskim:mentions | umls-concept:C1705165 | lld:lifeskim |
| pubmed-article:3134945 | lifeskim:mentions | umls-concept:C0086860 | lld:lifeskim |
| pubmed-article:3134945 | lifeskim:mentions | umls-concept:C0205250 | lld:lifeskim |
| pubmed-article:3134945 | lifeskim:mentions | umls-concept:C2700061 | lld:lifeskim |
| pubmed-article:3134945 | lifeskim:mentions | umls-concept:C0614284 | lld:lifeskim |
| pubmed-article:3134945 | lifeskim:mentions | umls-concept:C0071408 | lld:lifeskim |
| pubmed-article:3134945 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:3134945 | pubmed:dateCreated | 1988-8-30 | lld:pubmed |
| pubmed-article:3134945 | pubmed:abstractText | The effects of Ru(NH3)(3+)6 on the conformation of poly(dG-m5dC).poly(dG-m5dC) and poly(dG-dC).poly(dG-dC) were studied by circular dichroism (CD) spectroscopy. Ru(NH3)(3+)6 at very low concentrations provokes the Z-DNA conformation in both polynucleotides. In the presence of 50 mM NaCl, the concentration of Ru(NH3)(3+)6 at the midpoint of B to Z transition of poly(dG-m5dC).poly(dG-m5dC) is 4 microM compared to 5 microM for Co(NH3)(3+)6. The half-lives of B to Z transition of poly(dG-m5dC).poly(dG-m5dC) in the presence of 10 microM Ru(NH3)(3+)6 and Co(NHG3)(3+)6 are at 23 and 30 min, respectively. The concentration of Ru(NH3)(3+)6 at the midpoint of B to Z transition of poly(dG-dC).poly(dG-dC) is 50 microM. These results demonstrate that Ru(NH3)(3+)6 is a highly efficient trivalent cation for the induction of B to Z transition in poly(dG-m5dC).poly(dG-m5dC) and poly(dG-dC).poly(dG-dC). In contrast, Ru(NH3)(3+)6 has no significant effect on the conformation of calf thymus DNA, poly(dA-dT).poly(dA-dT) and poly(dA-dC).poly(dG-dT). | lld:pubmed |
| pubmed-article:3134945 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3134945 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3134945 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:3134945 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3134945 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3134945 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3134945 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3134945 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3134945 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3134945 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3134945 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3134945 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:3134945 | pubmed:issn | 0300-9084 | lld:pubmed |
| pubmed-article:3134945 | pubmed:author | pubmed-author:MessnerR PRP | lld:pubmed |
| pubmed-article:3134945 | pubmed:author | pubmed-author:ThomasT JTJ | lld:pubmed |
| pubmed-article:3134945 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3134945 | pubmed:volume | 70 | lld:pubmed |
| pubmed-article:3134945 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3134945 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3134945 | pubmed:pagination | 221-6 | lld:pubmed |
| pubmed-article:3134945 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:3134945 | pubmed:meshHeading | pubmed-meshheading:3134945-... | lld:pubmed |
| pubmed-article:3134945 | pubmed:meshHeading | pubmed-meshheading:3134945-... | lld:pubmed |
| pubmed-article:3134945 | pubmed:meshHeading | pubmed-meshheading:3134945-... | lld:pubmed |
| pubmed-article:3134945 | pubmed:meshHeading | pubmed-meshheading:3134945-... | lld:pubmed |
| pubmed-article:3134945 | pubmed:meshHeading | pubmed-meshheading:3134945-... | lld:pubmed |
| pubmed-article:3134945 | pubmed:meshHeading | pubmed-meshheading:3134945-... | lld:pubmed |
| pubmed-article:3134945 | pubmed:year | 1988 | lld:pubmed |
| pubmed-article:3134945 | pubmed:articleTitle | Hexammineruthenium (III) chloride: a highly efficient promoter of the B-DNA to Z-DNA transition of poly-(dG-m5dC).poly(dG-m5dC) and poly(dG-dC).poly(dG-dC). | lld:pubmed |
| pubmed-article:3134945 | pubmed:affiliation | Department of Medicine, University of Minnesota, Minneapolis 55455. | lld:pubmed |
| pubmed-article:3134945 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3134945 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3134945 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3134945 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3134945 | lld:pubmed |
