| pubmed-article:3125866 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3125866 | lifeskim:mentions | umls-concept:C0330390 | lld:lifeskim |
| pubmed-article:3125866 | lifeskim:mentions | umls-concept:C0021756 | lld:lifeskim |
| pubmed-article:3125866 | lifeskim:mentions | umls-concept:C0427526 | lld:lifeskim |
| pubmed-article:3125866 | lifeskim:mentions | umls-concept:C0034819 | lld:lifeskim |
| pubmed-article:3125866 | lifeskim:mentions | umls-concept:C0086597 | lld:lifeskim |
| pubmed-article:3125866 | lifeskim:mentions | umls-concept:C1511636 | lld:lifeskim |
| pubmed-article:3125866 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
| pubmed-article:3125866 | lifeskim:mentions | umls-concept:C1711351 | lld:lifeskim |
| pubmed-article:3125866 | lifeskim:mentions | umls-concept:C2698977 | lld:lifeskim |
| pubmed-article:3125866 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:3125866 | pubmed:dateCreated | 1988-4-14 | lld:pubmed |
| pubmed-article:3125866 | pubmed:abstractText | The interleukin 2 (IL 2) receptor was studied in three cases of large granular lymphocyte (LGL) lymphocytosis. All cases were nonreactive with anti-Tac monoclonal antibody (MoAb; recognizing the p55 alpha subunit of the IL 2 receptor). Sodium dodecyl sulfate (SDS)/polyacrylamide gel electrophoretic analysis (PAGE) of cells to which radio-labeled rIL 2 had been chemically crosslinked revealed uniform expression of the p70/75 beta subunit of the IL 2 receptor in the absence of the alpha subunit. Stimulation of this receptor with 2 nmol/L rIL 2 for five days led to acquisition of anti-CD3 redirected cytotoxicity. This was accompanied by a fivefold to tenfold elevation in the activity of intracellular N-alpha-benzyloxycarbonyl-L-lysine thiobenzyl esterase, an LGL granule marker enzyme. These effects of IL 2 did not require induction of the Tac peptide. | lld:pubmed |
| pubmed-article:3125866 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3125866 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3125866 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:3125866 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3125866 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3125866 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3125866 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3125866 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3125866 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3125866 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:3125866 | pubmed:issn | 0006-4971 | lld:pubmed |
| pubmed-article:3125866 | pubmed:author | pubmed-author:WeberJJ | lld:pubmed |
| pubmed-article:3125866 | pubmed:author | pubmed-author:SchechterG... | lld:pubmed |
| pubmed-article:3125866 | pubmed:author | pubmed-author:TrepelJ BJB | lld:pubmed |
| pubmed-article:3125866 | pubmed:author | pubmed-author:PoplackDD | lld:pubmed |
| pubmed-article:3125866 | pubmed:author | pubmed-author:PharesJ CJC | lld:pubmed |
| pubmed-article:3125866 | pubmed:author | pubmed-author:SausvilleEE | lld:pubmed |
| pubmed-article:3125866 | pubmed:author | pubmed-author:RosolenAA | lld:pubmed |
| pubmed-article:3125866 | pubmed:author | pubmed-author:ColamoniciO... | lld:pubmed |
| pubmed-article:3125866 | pubmed:author | pubmed-author:GressRR | lld:pubmed |
| pubmed-article:3125866 | pubmed:author | pubmed-author:QuinonesRR | lld:pubmed |
| pubmed-article:3125866 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3125866 | pubmed:volume | 71 | lld:pubmed |
| pubmed-article:3125866 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3125866 | pubmed:authorsComplete | N | lld:pubmed |
| pubmed-article:3125866 | pubmed:pagination | 825-8 | lld:pubmed |
| pubmed-article:3125866 | pubmed:dateRevised | 2004-11-17 | lld:pubmed |
| pubmed-article:3125866 | pubmed:meshHeading | pubmed-meshheading:3125866-... | lld:pubmed |
| pubmed-article:3125866 | pubmed:meshHeading | pubmed-meshheading:3125866-... | lld:pubmed |
| pubmed-article:3125866 | pubmed:meshHeading | pubmed-meshheading:3125866-... | lld:pubmed |
| pubmed-article:3125866 | pubmed:meshHeading | pubmed-meshheading:3125866-... | lld:pubmed |
| pubmed-article:3125866 | pubmed:meshHeading | pubmed-meshheading:3125866-... | lld:pubmed |
| pubmed-article:3125866 | pubmed:meshHeading | pubmed-meshheading:3125866-... | lld:pubmed |
| pubmed-article:3125866 | pubmed:meshHeading | pubmed-meshheading:3125866-... | lld:pubmed |
| pubmed-article:3125866 | pubmed:meshHeading | pubmed-meshheading:3125866-... | lld:pubmed |
| pubmed-article:3125866 | pubmed:year | 1988 | lld:pubmed |
| pubmed-article:3125866 | pubmed:articleTitle | The beta subunit of the interleukin-2 receptor mediates interleukin-2 induction of anti-CD3 redirected cytotoxic capability in large granular lymphocytes. | lld:pubmed |
| pubmed-article:3125866 | pubmed:affiliation | Laboratory of Pathology, National Cancer Institute--Naval Medical Oncology Branch, Bethesda, MD 20892. | lld:pubmed |
| pubmed-article:3125866 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3125866 | lld:pubmed |
