pubmed-article:309941 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:309941 | lifeskim:mentions | umls-concept:C0006675 | lld:lifeskim |
pubmed-article:309941 | lifeskim:mentions | umls-concept:C0034650 | lld:lifeskim |
pubmed-article:309941 | lifeskim:mentions | umls-concept:C0242697 | lld:lifeskim |
pubmed-article:309941 | lifeskim:mentions | umls-concept:C0231530 | lld:lifeskim |
pubmed-article:309941 | lifeskim:mentions | umls-concept:C0521116 | lld:lifeskim |
pubmed-article:309941 | pubmed:dateCreated | 1979-2-23 | lld:pubmed |
pubmed-article:309941 | pubmed:abstractText | 1. Voltage clamp experiments using the three micro-electrode voltage clamp technique were performed on sartorius muscles of the frog. 2. By blocking potassium currents with tetraethylammonium and replacing chloride ions with sulphate a slow inward current was detected. 3. The slow inward current is mainly carried by calcium, since it is abolished by cobalt and D-600, it depends on external calcium, and is not affected by removing external sodium or by tetrodotoxin (TTX). 4. The slow inward current has a mean threshold of -40 mV, reaches a mean maximum value at ca. 0 mV of 81 microamperemetercm-2 and has a mean reversal potential of +38 mV. 5. The calcium current is inactivated by the application of 2 sec conditioning prepulses according to a sigmoid curve with V(h) = -42 mV and k = 6.2 mV. 6. The slow time course of this calcium current makes it rather unlikely that it participates in contraction during a twitch, but it might be activated during long depolarizations as potassium contractures. | lld:pubmed |
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pubmed-article:309941 | pubmed:language | eng | lld:pubmed |
pubmed-article:309941 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:309941 | pubmed:citationSubset | IM | lld:pubmed |
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pubmed-article:309941 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:309941 | pubmed:month | Oct | lld:pubmed |
pubmed-article:309941 | pubmed:issn | 0022-3751 | lld:pubmed |
pubmed-article:309941 | pubmed:author | pubmed-author:StefaniEE | lld:pubmed |
pubmed-article:309941 | pubmed:author | pubmed-author:SanchezJ AJA | lld:pubmed |
pubmed-article:309941 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:309941 | pubmed:volume | 283 | lld:pubmed |
pubmed-article:309941 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:309941 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:309941 | pubmed:pagination | 197-209 | lld:pubmed |
pubmed-article:309941 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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pubmed-article:309941 | pubmed:year | 1978 | lld:pubmed |
pubmed-article:309941 | pubmed:articleTitle | Inward calcium current in twitch muscle fibres of the frog. | lld:pubmed |
pubmed-article:309941 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:309941 | pubmed:publicationType | In Vitro | lld:pubmed |
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