| pubmed-article:309370 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:309370 | lifeskim:mentions | umls-concept:C0302592 | lld:lifeskim |
| pubmed-article:309370 | lifeskim:mentions | umls-concept:C1257890 | lld:lifeskim |
| pubmed-article:309370 | lifeskim:mentions | umls-concept:C1522449 | lld:lifeskim |
| pubmed-article:309370 | lifeskim:mentions | umls-concept:C0007137 | lld:lifeskim |
| pubmed-article:309370 | lifeskim:mentions | umls-concept:C0004561 | lld:lifeskim |
| pubmed-article:309370 | lifeskim:mentions | umls-concept:C0205281 | lld:lifeskim |
| pubmed-article:309370 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:309370 | pubmed:dateCreated | 1979-1-26 | lld:pubmed |
| pubmed-article:309370 | pubmed:abstractText | Lymphocyte subpopulations in patients with cervical carcinoma were studied before and after radiotherapy. T lymphocytes were recognized by their ability to form spontaneous rosettes with sheep erythrocytes (E rosettes). Two surface marker characteristics were used to detect B lymphocytes: receptors for activated complement responsible for erythrocyte--antibody--complement (EAC) rosette formation, and surface membrane immunoglobulin (SmIg), readily stainable by immunofluorescence. We have demonstrated a significant depression of total lymphocytes after radiotherapy which persists for more than 5 years. This reduction in lymphocytes is due to a loss of E rosette-forming T cells, SmIg-bearing B cells and null cells. Absolute numbers of EAC rosette-forming B cells are not altered by treatment, and there is a rise in this cell type when the results are expressed as percentages of the total lymphocyte count. The possible functional immunological significance of these changes is discussed. | lld:pubmed |
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| pubmed-article:309370 | pubmed:language | eng | lld:pubmed |
| pubmed-article:309370 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:309370 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:309370 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:309370 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:309370 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:309370 | pubmed:issn | 0009-9104 | lld:pubmed |
| pubmed-article:309370 | pubmed:author | pubmed-author:JenkinsD MDM | lld:pubmed |
| pubmed-article:309370 | pubmed:author | pubmed-author:BulmerRR | lld:pubmed |
| pubmed-article:309370 | pubmed:author | pubmed-author:RandR JRJ | lld:pubmed |
| pubmed-article:309370 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:309370 | pubmed:volume | 33 | lld:pubmed |
| pubmed-article:309370 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:309370 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:309370 | pubmed:pagination | 159-65 | lld:pubmed |
| pubmed-article:309370 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:309370 | pubmed:year | 1978 | lld:pubmed |
| pubmed-article:309370 | pubmed:articleTitle | T- and B-lymphocyte subpopulations following radiotherapy for invasive squamous cell carcinoma of the uterine cervix. | lld:pubmed |
| pubmed-article:309370 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:309370 | lld:pubmed |
