pubmed-article:3089655 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:3089655 | lifeskim:mentions | umls-concept:C0015506 | lld:lifeskim |
pubmed-article:3089655 | lifeskim:mentions | umls-concept:C0542341 | lld:lifeskim |
pubmed-article:3089655 | lifeskim:mentions | umls-concept:C0259931 | lld:lifeskim |
pubmed-article:3089655 | lifeskim:mentions | umls-concept:C0205161 | lld:lifeskim |
pubmed-article:3089655 | lifeskim:mentions | umls-concept:C0443121 | lld:lifeskim |
pubmed-article:3089655 | lifeskim:mentions | umls-concept:C2003864 | lld:lifeskim |
pubmed-article:3089655 | lifeskim:mentions | umls-concept:C0332293 | lld:lifeskim |
pubmed-article:3089655 | pubmed:issue | 3 | lld:pubmed |
pubmed-article:3089655 | pubmed:dateCreated | 1986-9-17 | lld:pubmed |
pubmed-article:3089655 | pubmed:abstractText | B-Cell function was evaluated in a group of 43 patients with factor VIII or factor IX deficiency. Thirty had been treated primarily with cryoprecipitate and 13 with concentrates of factor VIII or IX. Serum immunoglobulin G levels were found to be diffusely elevated; however, the absolute number of mature B cells in peripheral blood was normal. B-Cell function as measured by testing mitogen-induced proliferation and and immunoglobulin secretion by plaque-forming cells (PFC) in vitro was reduced. Coculture experiments suggested that these abnormal B-cell responses might be secondary to increased suppressor T-cell activity, which was found more frequently in patients seropositive for antibody to lymphadenopathy-associated virus. Both seronegative and seropositive patients had reduced responses in the proliferative and PFC assays, but the lowest PFC responses occurred in the seropositive group. | lld:pubmed |
pubmed-article:3089655 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3089655 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3089655 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3089655 | pubmed:language | eng | lld:pubmed |
pubmed-article:3089655 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3089655 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:3089655 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3089655 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3089655 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3089655 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3089655 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3089655 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:3089655 | pubmed:month | Sep | lld:pubmed |
pubmed-article:3089655 | pubmed:issn | 0090-1229 | lld:pubmed |
pubmed-article:3089655 | pubmed:author | pubmed-author:MartinP JPJ | lld:pubmed |
pubmed-article:3089655 | pubmed:author | pubmed-author:HansenJ AJA | lld:pubmed |
pubmed-article:3089655 | pubmed:author | pubmed-author:GorskiAA | lld:pubmed |
pubmed-article:3089655 | pubmed:author | pubmed-author:CountsR BRB | lld:pubmed |
pubmed-article:3089655 | pubmed:author | pubmed-author:GjersetG FGF | lld:pubmed |
pubmed-article:3089655 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:3089655 | pubmed:volume | 40 | lld:pubmed |
pubmed-article:3089655 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:3089655 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:3089655 | pubmed:pagination | 447-55 | lld:pubmed |
pubmed-article:3089655 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
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pubmed-article:3089655 | pubmed:year | 1986 | lld:pubmed |
pubmed-article:3089655 | pubmed:articleTitle | Abnormal B-cell function in hemophiliacs treated with cryoprecipitate and factor VIII and IX concentrates. | lld:pubmed |
pubmed-article:3089655 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:3089655 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
pubmed-article:3089655 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3089655 | lld:pubmed |