| pubmed-article:3086365 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3086365 | lifeskim:mentions | umls-concept:C0041296 | lld:lifeskim |
| pubmed-article:3086365 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:3086365 | lifeskim:mentions | umls-concept:C0229664 | lld:lifeskim |
| pubmed-article:3086365 | lifeskim:mentions | umls-concept:C0023516 | lld:lifeskim |
| pubmed-article:3086365 | lifeskim:mentions | umls-concept:C0021745 | lld:lifeskim |
| pubmed-article:3086365 | lifeskim:mentions | umls-concept:C0205178 | lld:lifeskim |
| pubmed-article:3086365 | lifeskim:mentions | umls-concept:C0033268 | lld:lifeskim |
| pubmed-article:3086365 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:3086365 | pubmed:dateCreated | 1986-6-27 | lld:pubmed |
| pubmed-article:3086365 | pubmed:abstractText | Production of interferon (IFN)-gamma by peripheral blood leukocytes (PBL) was examined in cultures of unseparated fresh whole blood exposed to phytohemagglutinin (PHA), concanavalin A (Con A), or pokeweed mitogen (PWM). The yield of IFN-gamma was measured by a newly developed immunoradiometric assay. Nine of 14 patients with acute pulmonary tuberculosis (TB) showed a depressed IFN-gamma response to Con A and/or PWM. Only four of these TB patients also showed a depressed IFN-gamma response to PHA. Stimulation of the patients' PBL cultures with PHA in the presence of exogenous interleukin 2 (IL 2) produced normal IFN-gamma yields in all but the most severely depressed patients. PBL cultures of TB patients with defective IFN-gamma production in response to mitogenic lectins also produced less IFN-gamma after stimulation with tuberculin PPD. Although some patients showed a moderate degree of lymphopenia, their OKT4/T8 lymphocyte ratios were mostly normal or close to normal, with the notable exception of one TB patient who has been diagnosed to have the acquired immune deficiency syndrome (AIDS). | lld:pubmed |
| pubmed-article:3086365 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3086365 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3086365 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3086365 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3086365 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:3086365 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3086365 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3086365 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:3086365 | pubmed:issn | 0271-9142 | lld:pubmed |
| pubmed-article:3086365 | pubmed:author | pubmed-author:DavidsonMM | lld:pubmed |
| pubmed-article:3086365 | pubmed:author | pubmed-author:VilcekJJ | lld:pubmed |
| pubmed-article:3086365 | pubmed:author | pubmed-author:Friedman-Kien... | lld:pubmed |
| pubmed-article:3086365 | pubmed:author | pubmed-author:DavidsonD MDM | lld:pubmed |
| pubmed-article:3086365 | pubmed:author | pubmed-author:DAYG HGH | lld:pubmed |
| pubmed-article:3086365 | pubmed:author | pubmed-author:ZemtsovAA | lld:pubmed |
| pubmed-article:3086365 | pubmed:author | pubmed-author:Henriksen-DeS... | lld:pubmed |
| pubmed-article:3086365 | pubmed:author | pubmed-author:KlionAA | lld:pubmed |
| pubmed-article:3086365 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3086365 | pubmed:volume | 6 | lld:pubmed |
| pubmed-article:3086365 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3086365 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3086365 | pubmed:pagination | 146-51 | lld:pubmed |
| pubmed-article:3086365 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
| pubmed-article:3086365 | pubmed:meshHeading | pubmed-meshheading:3086365-... | lld:pubmed |
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| pubmed-article:3086365 | pubmed:meshHeading | pubmed-meshheading:3086365-... | lld:pubmed |
| pubmed-article:3086365 | pubmed:meshHeading | pubmed-meshheading:3086365-... | lld:pubmed |
| pubmed-article:3086365 | pubmed:meshHeading | pubmed-meshheading:3086365-... | lld:pubmed |
| pubmed-article:3086365 | pubmed:meshHeading | pubmed-meshheading:3086365-... | lld:pubmed |
| pubmed-article:3086365 | pubmed:meshHeading | pubmed-meshheading:3086365-... | lld:pubmed |
| pubmed-article:3086365 | pubmed:year | 1986 | lld:pubmed |
| pubmed-article:3086365 | pubmed:articleTitle | Defective gamma-interferon production in peripheral blood leukocytes of patients with acute tuberculosis. | lld:pubmed |
| pubmed-article:3086365 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3086365 | pubmed:publicationType | In Vitro | lld:pubmed |
| pubmed-article:3086365 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:3086365 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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