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pubmed-article:3038106pubmed:abstractTextA surgically removed human stomach cancer with the histological diagnosis of poorly differentiated adenocarcinoma contained an activated N-ras oncogene detected by an in vivo selection assay in nude mice using transfected NIH3T3 cells. Analysis using synthetic 20-mer oligonucleotide probes revealed a point mutation from G to C at the first letter of codon 13 of the N-ras gene resulting in the substitution of arginine for glycine. This is the first observation of an activated N-ras oncogene in human stomach cancers.lld:pubmed
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pubmed-article:3038106pubmed:articleTitleA point mutation at codon 13 of the N-ras oncogene in a human stomach cancer.lld:pubmed
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