| pubmed-article:3027634 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3027634 | lifeskim:mentions | umls-concept:C0684249 | lld:lifeskim |
| pubmed-article:3027634 | lifeskim:mentions | umls-concept:C0011923 | lld:lifeskim |
| pubmed-article:3027634 | lifeskim:mentions | umls-concept:C0003250 | lld:lifeskim |
| pubmed-article:3027634 | lifeskim:mentions | umls-concept:C0205225 | lld:lifeskim |
| pubmed-article:3027634 | pubmed:issue | 10 | lld:pubmed |
| pubmed-article:3027634 | pubmed:dateCreated | 1987-3-6 | lld:pubmed |
| pubmed-article:3027634 | pubmed:abstractText | Preliminary clinical studies have been carried out to determine whether the monoclonal antibody 791T/36 would localize in primary lung cancer to an extent sufficient for external detection by gamma scintigraphy. Radiolabelling of the antibody with 131I permitted visualization of three out of eight (38%) tumours using planar imaging with 99Tcm-labelled blood pool subtraction. Radiolabelling of the same antibody with 111In permitted visualization of tumour uptake in nine out of 13 (69%) tumours, without the need for image subtraction. Single photon emission computed tomography (SPECT) studies of seven patients demonstrated concentration of 111In-labelled antibody at the tumour site in each case, four of which were visualized on the planar images. The present study demonstrates localization of the 791T/36 antibody in primary lung carcinoma and confirms the superiority of 111In over 131I as a radiolabel for antibody imaging, especially when emission tomography is performed. These data indicate that further work will be required to determine whether this antibody will be a suitable carrier for cytotoxic agents in the therapy of lung cancer. | lld:pubmed |
| pubmed-article:3027634 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3027634 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3027634 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:3027634 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3027634 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3027634 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3027634 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3027634 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3027634 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:3027634 | pubmed:issn | 0143-3636 | lld:pubmed |
| pubmed-article:3027634 | pubmed:author | pubmed-author:PimmM VMV | lld:pubmed |
| pubmed-article:3027634 | pubmed:author | pubmed-author:BaldwinR WRW | lld:pubmed |
| pubmed-article:3027634 | pubmed:author | pubmed-author:MorganD ADA | lld:pubmed |
| pubmed-article:3027634 | pubmed:author | pubmed-author:ReynoldsJ RJR | lld:pubmed |
| pubmed-article:3027634 | pubmed:author | pubmed-author:WastieM LML | lld:pubmed |
| pubmed-article:3027634 | pubmed:author | pubmed-author:PerkinsA CAC | lld:pubmed |
| pubmed-article:3027634 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3027634 | pubmed:volume | 7 | lld:pubmed |
| pubmed-article:3027634 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3027634 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3027634 | pubmed:pagination | 729-39 | lld:pubmed |
| pubmed-article:3027634 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:3027634 | pubmed:meshHeading | pubmed-meshheading:3027634-... | lld:pubmed |
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| pubmed-article:3027634 | pubmed:meshHeading | pubmed-meshheading:3027634-... | lld:pubmed |
| pubmed-article:3027634 | pubmed:meshHeading | pubmed-meshheading:3027634-... | lld:pubmed |
| pubmed-article:3027634 | pubmed:meshHeading | pubmed-meshheading:3027634-... | lld:pubmed |
| pubmed-article:3027634 | pubmed:meshHeading | pubmed-meshheading:3027634-... | lld:pubmed |
| pubmed-article:3027634 | pubmed:meshHeading | pubmed-meshheading:3027634-... | lld:pubmed |
| pubmed-article:3027634 | pubmed:meshHeading | pubmed-meshheading:3027634-... | lld:pubmed |
| pubmed-article:3027634 | pubmed:meshHeading | pubmed-meshheading:3027634-... | lld:pubmed |
| pubmed-article:3027634 | pubmed:year | 1986 | lld:pubmed |
| pubmed-article:3027634 | pubmed:articleTitle | 131I and 111In-labelled monoclonal antibody imaging of primary lung carcinoma. | lld:pubmed |
| pubmed-article:3027634 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3027634 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3027634 | lld:pubmed |
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| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3027634 | lld:pubmed |
