| pubmed-article:3027566 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3027566 | lifeskim:mentions | umls-concept:C0038975 | lld:lifeskim |
| pubmed-article:3027566 | lifeskim:mentions | umls-concept:C0017337 | lld:lifeskim |
| pubmed-article:3027566 | lifeskim:mentions | umls-concept:C0021034 | lld:lifeskim |
| pubmed-article:3027566 | lifeskim:mentions | umls-concept:C0040648 | lld:lifeskim |
| pubmed-article:3027566 | lifeskim:mentions | umls-concept:C0041526 | lld:lifeskim |
| pubmed-article:3027566 | lifeskim:mentions | umls-concept:C0086222 | lld:lifeskim |
| pubmed-article:3027566 | lifeskim:mentions | umls-concept:C1145667 | lld:lifeskim |
| pubmed-article:3027566 | lifeskim:mentions | umls-concept:C1705733 | lld:lifeskim |
| pubmed-article:3027566 | pubmed:issue | 6101 | lld:pubmed |
| pubmed-article:3027566 | pubmed:dateCreated | 1987-2-26 | lld:pubmed |
| pubmed-article:3027566 | pubmed:abstractText | In eukaryotes the transcriptional control of RNA polymerase II-mediated gene expression is exerted by cis-acting regulatory DNA elements classified as promoter and enhancer sequences. These elements are composed of a number of different protein binding sites. The regulatory factors that recognize such 'modules' may be ubiquitous, tissue- or stage-specific, and positively or negatively acting. According to this model the transcriptional activity of a given gene is programmed by a combination of different modules. We analysed such a site of protein-DNA interaction, the octamer motif, in the enhancers of the simian virus (SV40) early genes and the murine immunoglobulin heavy-chain gene, and in the distal sequence element (DSE) of the U2 small nuclear (sn)RNA gene of Xenopus laevis. The corresponding DNA-binding factor appears to be the same in the three cases. Moreover, a fraction containing partially purified octamer motif binding factor has a stimulatory effect on transcription in an in vitro system. | lld:pubmed |
| pubmed-article:3027566 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3027566 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3027566 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:3027566 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:3027566 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3027566 | pubmed:issn | 0028-0836 | lld:pubmed |
| pubmed-article:3027566 | pubmed:author | pubmed-author:KellerWW | lld:pubmed |
| pubmed-article:3027566 | pubmed:author | pubmed-author:MattajI WIW | lld:pubmed |
| pubmed-article:3027566 | pubmed:author | pubmed-author:BohmannDD | lld:pubmed |
| pubmed-article:3027566 | pubmed:author | pubmed-author:TebbGG | lld:pubmed |
| pubmed-article:3027566 | pubmed:author | pubmed-author:SchölerH RHR | lld:pubmed |
| pubmed-article:3027566 | pubmed:author | pubmed-author:DaleTT | lld:pubmed |
| pubmed-article:3027566 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3027566 | pubmed:volume | 325 | lld:pubmed |
| pubmed-article:3027566 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3027566 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3027566 | pubmed:pagination | 268-72 | lld:pubmed |
| pubmed-article:3027566 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
| pubmed-article:3027566 | pubmed:meshHeading | pubmed-meshheading:3027566-... | lld:pubmed |
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| pubmed-article:3027566 | pubmed:meshHeading | pubmed-meshheading:3027566-... | lld:pubmed |
| pubmed-article:3027566 | pubmed:articleTitle | A transcription factor which binds to the enhancers of SV40, immunoglobulin heavy chain and U2 snRNA genes. | lld:pubmed |
| pubmed-article:3027566 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3027566 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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