| pubmed-article:3011404 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3011404 | lifeskim:mentions | umls-concept:C0030354 | lld:lifeskim |
| pubmed-article:3011404 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:3011404 | lifeskim:mentions | umls-concept:C0020792 | lld:lifeskim |
| pubmed-article:3011404 | lifeskim:mentions | umls-concept:C0033684 | lld:lifeskim |
| pubmed-article:3011404 | lifeskim:mentions | umls-concept:C1704222 | lld:lifeskim |
| pubmed-article:3011404 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:3011404 | pubmed:dateCreated | 1986-6-30 | lld:pubmed |
| pubmed-article:3011404 | pubmed:abstractText | Antibodies prepared against a human papilloma virus-1 (HPV-1) E4/beta-galactosidase fusion protein identified several polypeptides in HPV-1, but not HPV-2 or 4, induced papillomas. The major E4 protein, that represented up to 30% of total cellular protein, was a 16/17-K doublet which was purified by column chromatography and analysed for amino acid content. A peptide derived by chymotryptic digestion was purified by h.p.l.c. and subjected to amino acid sequencing. The unique sequence obtained, Gly-His-Pro-Asp-Leu-Ser-Leu, identified the 16/17-K doublet as a product of the HPV-1 E4 gene region. Antibodies to both the E4/beta-galactosidase fusion protein and the 16/17-K doublet identified two smaller polypeptides (10/11-K) which may represent spliced products of E4. We propose that the products of the HPV-1 E4 gene region are not classical DNA tumor virus early proteins and suggest that they play a role in virus maturation. | lld:pubmed |
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| pubmed-article:3011404 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:3011404 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:3011404 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3011404 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:3011404 | pubmed:issn | 0261-4189 | lld:pubmed |
| pubmed-article:3011404 | pubmed:author | pubmed-author:GrandR JRJ | lld:pubmed |
| pubmed-article:3011404 | pubmed:author | pubmed-author:CampbellDD | lld:pubmed |
| pubmed-article:3011404 | pubmed:author | pubmed-author:GallimoreP... | lld:pubmed |
| pubmed-article:3011404 | pubmed:author | pubmed-author:DoorbarJJ | lld:pubmed |
| pubmed-article:3011404 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3011404 | pubmed:volume | 5 | lld:pubmed |
| pubmed-article:3011404 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3011404 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3011404 | pubmed:pagination | 355-62 | lld:pubmed |
| pubmed-article:3011404 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:3011404 | pubmed:year | 1986 | lld:pubmed |
| pubmed-article:3011404 | pubmed:articleTitle | Identification of the human papilloma virus-1a E4 gene products. | lld:pubmed |
| pubmed-article:3011404 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3011404 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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