| pubmed-article:3010305 | rdf:type | pubmed:Citation | lld:pubmed |
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| pubmed-article:3010305 | lifeskim:mentions | umls-concept:C1704684 | lld:lifeskim |
| pubmed-article:3010305 | lifeskim:mentions | umls-concept:C0314603 | lld:lifeskim |
| pubmed-article:3010305 | lifeskim:mentions | umls-concept:C0013139 | lld:lifeskim |
| pubmed-article:3010305 | lifeskim:mentions | umls-concept:C0180860 | lld:lifeskim |
| pubmed-article:3010305 | lifeskim:mentions | umls-concept:C0581406 | lld:lifeskim |
| pubmed-article:3010305 | lifeskim:mentions | umls-concept:C1522664 | lld:lifeskim |
| pubmed-article:3010305 | lifeskim:mentions | umls-concept:C1550638 | lld:lifeskim |
| pubmed-article:3010305 | lifeskim:mentions | umls-concept:C0868946 | lld:lifeskim |
| pubmed-article:3010305 | pubmed:issue | 10 | lld:pubmed |
| pubmed-article:3010305 | pubmed:dateCreated | 1986-6-23 | lld:pubmed |
| pubmed-article:3010305 | pubmed:abstractText | A filter hybridization method is described for identifying restriction-site and insertion/deletion variation by using restriction enzymes that recognize four-nucleotide sequences and denaturing polyacrylamide gels for separating fragments. Eighty-seven lines of Drosophila melanogaster representing two natural populations were surveyed over a 2.7-kilobase region encompassing the alcohol dehydrogenase locus. Fifty distinct haplotypes were identified from 17 restriction-site and 11 insertion/deletion polymorphisms and from one allozyme polymorphism. There was no evidence for genetic differentiation between an East-Coast and a West-Coast (North American) sample. This technique has widespread applications in screening for DNA polymorphism. | lld:pubmed |
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| pubmed-article:3010305 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3010305 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3010305 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:3010305 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3010305 | pubmed:month | May | lld:pubmed |
| pubmed-article:3010305 | pubmed:issn | 0027-8424 | lld:pubmed |
| pubmed-article:3010305 | pubmed:author | pubmed-author:AguadéMM | lld:pubmed |
| pubmed-article:3010305 | pubmed:author | pubmed-author:KreitmanMM | lld:pubmed |
| pubmed-article:3010305 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3010305 | pubmed:volume | 83 | lld:pubmed |
| pubmed-article:3010305 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3010305 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3010305 | pubmed:pagination | 3562-6 | lld:pubmed |
| pubmed-article:3010305 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:3010305 | pubmed:year | 1986 | lld:pubmed |
| pubmed-article:3010305 | pubmed:articleTitle | Genetic uniformity in two populations of Drosophila melanogaster as revealed by filter hybridization of four-nucleotide-recognizing restriction enzyme digests. | lld:pubmed |
| pubmed-article:3010305 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3010305 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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