| pubmed-article:3007120 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3007120 | lifeskim:mentions | umls-concept:C0007634 | lld:lifeskim |
| pubmed-article:3007120 | lifeskim:mentions | umls-concept:C0004561 | lld:lifeskim |
| pubmed-article:3007120 | lifeskim:mentions | umls-concept:C0035668 | lld:lifeskim |
| pubmed-article:3007120 | lifeskim:mentions | umls-concept:C0012893 | lld:lifeskim |
| pubmed-article:3007120 | lifeskim:mentions | umls-concept:C0162788 | lld:lifeskim |
| pubmed-article:3007120 | lifeskim:mentions | umls-concept:C0205171 | lld:lifeskim |
| pubmed-article:3007120 | lifeskim:mentions | umls-concept:C1881379 | lld:lifeskim |
| pubmed-article:3007120 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:3007120 | pubmed:dateCreated | 1986-5-14 | lld:pubmed |
| pubmed-article:3007120 | pubmed:abstractText | A method for in situ hybridization has been developed which detects immunoglobulin-specific mRNA transcripts in single murine B lymphocytes with radiolabelled, immunoglobulin gene-specific single-stranded DNA probes. The method has been applied to myeloma and hybridoma cells and to B lymphocytes at various stages of their maturation from small, resting B cells to Ig-secreting plasma cells. A critical step in the procedure is the treatment of the cells with pronase. The various cell types have been found to be differently susceptible to this treatment. Single-stranded DNA probes of different lengths, i.e., between 26 and 1000 bp, have been employed in the hybridization. The number of silver grains over a cell increases proportionally with the length of the probe and with its concentration in the hybridization reaction. The kinetics of the increase of mu-heavy chain-specific RNA molecules in single cells and the appearance of 'switched', gamma-heavy chain-expressing cells are shown after stimulation of murine B cells with lipopolysaccharide. | lld:pubmed |
| pubmed-article:3007120 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3007120 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3007120 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3007120 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3007120 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3007120 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3007120 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3007120 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3007120 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3007120 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3007120 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3007120 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3007120 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3007120 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3007120 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3007120 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3007120 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3007120 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3007120 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3007120 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3007120 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3007120 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3007120 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3007120 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3007120 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3007120 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3007120 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3007120 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3007120 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3007120 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3007120 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3007120 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3007120 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3007120 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3007120 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3007120 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3007120 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3007120 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3007120 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:3007120 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3007120 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3007120 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3007120 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3007120 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3007120 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3007120 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:3007120 | pubmed:issn | 0261-4189 | lld:pubmed |
| pubmed-article:3007120 | pubmed:author | pubmed-author:BergerC NCN | lld:pubmed |
| pubmed-article:3007120 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3007120 | pubmed:volume | 5 | lld:pubmed |
| pubmed-article:3007120 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3007120 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3007120 | pubmed:pagination | 85-93 | lld:pubmed |
| pubmed-article:3007120 | pubmed:dateRevised | 2010-9-9 | lld:pubmed |
| pubmed-article:3007120 | pubmed:meshHeading | pubmed-meshheading:3007120-... | lld:pubmed |
| pubmed-article:3007120 | pubmed:meshHeading | pubmed-meshheading:3007120-... | lld:pubmed |
| pubmed-article:3007120 | pubmed:meshHeading | pubmed-meshheading:3007120-... | lld:pubmed |
| pubmed-article:3007120 | pubmed:meshHeading | pubmed-meshheading:3007120-... | lld:pubmed |
| pubmed-article:3007120 | pubmed:meshHeading | pubmed-meshheading:3007120-... | lld:pubmed |
| pubmed-article:3007120 | pubmed:meshHeading | pubmed-meshheading:3007120-... | lld:pubmed |
| pubmed-article:3007120 | pubmed:meshHeading | pubmed-meshheading:3007120-... | lld:pubmed |
| pubmed-article:3007120 | pubmed:meshHeading | pubmed-meshheading:3007120-... | lld:pubmed |
| pubmed-article:3007120 | pubmed:meshHeading | pubmed-meshheading:3007120-... | lld:pubmed |
| pubmed-article:3007120 | pubmed:meshHeading | pubmed-meshheading:3007120-... | lld:pubmed |
| pubmed-article:3007120 | pubmed:meshHeading | pubmed-meshheading:3007120-... | lld:pubmed |
| pubmed-article:3007120 | pubmed:meshHeading | pubmed-meshheading:3007120-... | lld:pubmed |
| pubmed-article:3007120 | pubmed:meshHeading | pubmed-meshheading:3007120-... | lld:pubmed |
| pubmed-article:3007120 | pubmed:meshHeading | pubmed-meshheading:3007120-... | lld:pubmed |
| pubmed-article:3007120 | pubmed:year | 1986 | lld:pubmed |
| pubmed-article:3007120 | pubmed:articleTitle | In situ hybridization of immunoglobulin-specific RNA in single cells of the B lymphocyte lineage with radiolabelled DNA probes. | lld:pubmed |
| pubmed-article:3007120 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3007120 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3007120 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3007120 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3007120 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3007120 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3007120 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3007120 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3007120 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3007120 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3007120 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3007120 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3007120 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3007120 | lld:pubmed |
