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| pubmed-article:2998762 | lifeskim:mentions | umls-concept:C0029016 | lld:lifeskim |
| pubmed-article:2998762 | lifeskim:mentions | umls-concept:C0929301 | lld:lifeskim |
| pubmed-article:2998762 | lifeskim:mentions | umls-concept:C0006141 | lld:lifeskim |
| pubmed-article:2998762 | lifeskim:mentions | umls-concept:C0004793 | lld:lifeskim |
| pubmed-article:2998762 | lifeskim:mentions | umls-concept:C0162326 | lld:lifeskim |
| pubmed-article:2998762 | lifeskim:mentions | umls-concept:C0009219 | lld:lifeskim |
| pubmed-article:2998762 | lifeskim:mentions | umls-concept:C2347858 | lld:lifeskim |
| pubmed-article:2998762 | pubmed:issue | 11 | lld:pubmed |
| pubmed-article:2998762 | pubmed:dateCreated | 1986-1-23 | lld:pubmed |
| pubmed-article:2998762 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2998762 | pubmed:abstractText | The mouse mammary tumor virus can induce mammary tumors in mice by proviral activation of an evolutionarily conserved cellular oncogene called int-1. Here we present the nucleotide sequence of the human homologue of int-1, and compare it with the mouse gene. Like the mouse gene, the human homologue contains a reading frame of 370 amino acids, with only four substitutions. The amino acid changes are all in the hydrophobic leader domain of the int-1 encoded protein, and do not significantly alter its hydropathic index. The conservation between the mouse and the human int-1 genes is not restricted to exons; extensive parts of the introns are also homologous. Thus, int-1 ranks among the most conserved genes known, a property shared with other oncogenes. | lld:pubmed |
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| pubmed-article:2998762 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2998762 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2998762 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:2998762 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2998762 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:2998762 | pubmed:issn | 0261-4189 | lld:pubmed |
| pubmed-article:2998762 | pubmed:author | pubmed-author:NusseRR | lld:pubmed |
| pubmed-article:2998762 | pubmed:author | pubmed-author:van OoyenAA | lld:pubmed |
| pubmed-article:2998762 | pubmed:author | pubmed-author:KweeVV | lld:pubmed |
| pubmed-article:2998762 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2998762 | pubmed:volume | 4 | lld:pubmed |
| pubmed-article:2998762 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2998762 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2998762 | pubmed:pagination | 2905-9 | lld:pubmed |
| pubmed-article:2998762 | pubmed:dateRevised | 2010-11-18 | lld:pubmed |
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| pubmed-article:2998762 | pubmed:year | 1985 | lld:pubmed |
| pubmed-article:2998762 | pubmed:articleTitle | The nucleotide sequence of the human int-1 mammary oncogene; evolutionary conservation of coding and non-coding sequences. | lld:pubmed |
| pubmed-article:2998762 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2998762 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:2998762 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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