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| pubmed-article:2986545 | lifeskim:mentions | umls-concept:C0022209 | lld:lifeskim |
| pubmed-article:2986545 | lifeskim:mentions | umls-concept:C0162772 | lld:lifeskim |
| pubmed-article:2986545 | lifeskim:mentions | umls-concept:C2828366 | lld:lifeskim |
| pubmed-article:2986545 | lifeskim:mentions | umls-concept:C1705851 | lld:lifeskim |
| pubmed-article:2986545 | lifeskim:mentions | umls-concept:C0079411 | lld:lifeskim |
| pubmed-article:2986545 | lifeskim:mentions | umls-concept:C1555707 | lld:lifeskim |
| pubmed-article:2986545 | lifeskim:mentions | umls-concept:C0332120 | lld:lifeskim |
| pubmed-article:2986545 | lifeskim:mentions | umls-concept:C2752151 | lld:lifeskim |
| pubmed-article:2986545 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:2986545 | pubmed:dateCreated | 1985-6-10 | lld:pubmed |
| pubmed-article:2986545 | pubmed:abstractText | Crude extracts of Mycobacterium tuberculosis H37Ra, an isonicotinic acid hydrazide (isoniazid) (INH)-susceptible strain which has peroxidase activity, catalyzed the production of catechol from phenol in the presence of INH and H2O2 as shown by the development of the 444-nm absorption peak of oxidized catechol product. Extracts of the INH-resistant strain of M. tuberculosis H37Ra, which has no peroxidase, did not catalyze the reaction. The rate of development of the 444-nm peak increased proportionately with increased superoxide dismutase concentrations. The hydroxyl radical (. OH) scavengers dimethylsulfoxide and mannitol inhibited the reaction. Isonicotinamide, isonicotinic acid, and nicotinic acid could not replace INH. | lld:pubmed |
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| pubmed-article:2986545 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:2986545 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:2986545 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2986545 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:2986545 | pubmed:issn | 0066-4804 | lld:pubmed |
| pubmed-article:2986545 | pubmed:author | pubmed-author:ShoebH AHA | lld:pubmed |
| pubmed-article:2986545 | pubmed:author | pubmed-author:OttolenghiA... | lld:pubmed |
| pubmed-article:2986545 | pubmed:author | pubmed-author:BowmanB UBUJr | lld:pubmed |
| pubmed-article:2986545 | pubmed:author | pubmed-author:MerolaA JAJ | lld:pubmed |
| pubmed-article:2986545 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2986545 | pubmed:volume | 27 | lld:pubmed |
| pubmed-article:2986545 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2986545 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2986545 | pubmed:pagination | 404-7 | lld:pubmed |
| pubmed-article:2986545 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:2986545 | pubmed:year | 1985 | lld:pubmed |
| pubmed-article:2986545 | pubmed:articleTitle | Evidence for the generation of active oxygen by isoniazid treatment of extracts of Mycobacterium tuberculosis H37Ra. | lld:pubmed |
| pubmed-article:2986545 | pubmed:publicationType | Journal Article | lld:pubmed |
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