| pubmed-article:2973658 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2973658 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:2973658 | lifeskim:mentions | umls-concept:C0039194 | lld:lifeskim |
| pubmed-article:2973658 | lifeskim:mentions | umls-concept:C0014939 | lld:lifeskim |
| pubmed-article:2973658 | lifeskim:mentions | umls-concept:C0597357 | lld:lifeskim |
| pubmed-article:2973658 | lifeskim:mentions | umls-concept:C0205369 | lld:lifeskim |
| pubmed-article:2973658 | lifeskim:mentions | umls-concept:C1511636 | lld:lifeskim |
| pubmed-article:2973658 | lifeskim:mentions | umls-concept:C1515021 | lld:lifeskim |
| pubmed-article:2973658 | lifeskim:mentions | umls-concept:C0150312 | lld:lifeskim |
| pubmed-article:2973658 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:2973658 | pubmed:dateCreated | 1988-12-27 | lld:pubmed |
| pubmed-article:2973658 | pubmed:abstractText | Human spleen cells were investigated for specific oestrogen binding using oestradiol-17 beta. High affinity, low capacity binding was observed (Kd = 2.5 X 10(-10) M) and the characteristics of the oestrogen receptor identified were typical of this type of species. T lymphocyte subpopulations were prepared by negative selection by means of the monoclonal antibodies Leu 2a and 3a. Oestrogen receptors were only found in T cells of the suppressor/cytotoxic (CD8-positive) subset while helper/inducer lymphocytes (CD4-positive) showed no significant steroid binding by cytosol and nuclear assays. These results are supported by data from experiments into the effects of oestradiol-17 beta on immunoglobulin secretion, where it was apparent that only the suppressor/cytotoxic T-cell subpopulation was responsive to the presence of the steroid. | lld:pubmed |
| pubmed-article:2973658 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2973658 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2973658 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:2973658 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2973658 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:2973658 | pubmed:issn | 0300-9475 | lld:pubmed |
| pubmed-article:2973658 | pubmed:author | pubmed-author:StimsonW HWH | lld:pubmed |
| pubmed-article:2973658 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2973658 | pubmed:volume | 28 | lld:pubmed |
| pubmed-article:2973658 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2973658 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2973658 | pubmed:pagination | 345-50 | lld:pubmed |
| pubmed-article:2973658 | pubmed:dateRevised | 2005-11-17 | lld:pubmed |
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| pubmed-article:2973658 | pubmed:meshHeading | pubmed-meshheading:2973658-... | lld:pubmed |
| pubmed-article:2973658 | pubmed:year | 1988 | lld:pubmed |
| pubmed-article:2973658 | pubmed:articleTitle | Oestrogen and human T lymphocytes: presence of specific receptors in the T-suppressor/cytotoxic subset. | lld:pubmed |
| pubmed-article:2973658 | pubmed:affiliation | Immunology Division, Strathclyde University, Glasgow, UK. | lld:pubmed |
| pubmed-article:2973658 | pubmed:publicationType | Journal Article | lld:pubmed |
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