pubmed-article:2972781 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:2972781 | lifeskim:mentions | umls-concept:C0017337 | lld:lifeskim |
pubmed-article:2972781 | lifeskim:mentions | umls-concept:C0026249 | lld:lifeskim |
pubmed-article:2972781 | lifeskim:mentions | umls-concept:C1704632 | lld:lifeskim |
pubmed-article:2972781 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
pubmed-article:2972781 | lifeskim:mentions | umls-concept:C0871261 | lld:lifeskim |
pubmed-article:2972781 | lifeskim:mentions | umls-concept:C0314603 | lld:lifeskim |
pubmed-article:2972781 | lifeskim:mentions | umls-concept:C2911692 | lld:lifeskim |
pubmed-article:2972781 | lifeskim:mentions | umls-concept:C1706817 | lld:lifeskim |
pubmed-article:2972781 | lifeskim:mentions | umls-concept:C0443288 | lld:lifeskim |
pubmed-article:2972781 | lifeskim:mentions | umls-concept:C1515895 | lld:lifeskim |
pubmed-article:2972781 | lifeskim:mentions | umls-concept:C1521840 | lld:lifeskim |
pubmed-article:2972781 | pubmed:issue | 11 | lld:pubmed |
pubmed-article:2972781 | pubmed:dateCreated | 1988-12-20 | lld:pubmed |
pubmed-article:2972781 | pubmed:abstractText | The response of Bcgr and Bcgs spleen cells to allogeneic Ag, mitogens, and in a system of oxidative mitogenesis using neuraminidase and galactose oxidase was investigated in two Bcg congenic systems. The Bcgr macrophages supported the MLR across H-2 barrier much better than the Bcgs macrophages. At sub-optimal or optimal doses of mitogens Bcgr mice were higher responders than their Bcgs counterparts. The superior response of Bcgr spleen cells to Con A was further investigated with the aim of identifying the population expressing this phenotype. T cells of either Bcgr or Bcgs type showed equal ability to respond to Con A in the presence of macrophages. Purified splenic macrophages from Bcgr mice contained a significantly greater percentage of Ia+-bearing macrophages compared to Bcgs mice. Splenic macrophages of the Bcgr type were more efficient than their Bcgs counterparts at restoring the Con A response of accessory cell-depleted spleen cells. Resident peritoneal macrophages as well as splenic dendritic cells from Bcgr and Bcgs mice were equally efficient at restoring this response. Glutaraldehyde-fixed Bcgr splenic macrophages were shown to be more efficient than the Bcgs cells at replenishing the response of Con A-unresponsive spleen cells when supplemented with IL-1. | lld:pubmed |
pubmed-article:2972781 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2972781 | pubmed:language | eng | lld:pubmed |
pubmed-article:2972781 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2972781 | pubmed:citationSubset | AIM | lld:pubmed |
pubmed-article:2972781 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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pubmed-article:2972781 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:2972781 | pubmed:month | Dec | lld:pubmed |
pubmed-article:2972781 | pubmed:issn | 0022-1767 | lld:pubmed |
pubmed-article:2972781 | pubmed:author | pubmed-author:SkameneEE | lld:pubmed |
pubmed-article:2972781 | pubmed:author | pubmed-author:ForgetAA | lld:pubmed |
pubmed-article:2972781 | pubmed:author | pubmed-author:PelletierMM | lld:pubmed |
pubmed-article:2972781 | pubmed:author | pubmed-author:DenisMM | lld:pubmed |
pubmed-article:2972781 | pubmed:author | pubmed-author:BuschmanEE | lld:pubmed |
pubmed-article:2972781 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:2972781 | pubmed:day | 1 | lld:pubmed |
pubmed-article:2972781 | pubmed:volume | 141 | lld:pubmed |
pubmed-article:2972781 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:2972781 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:2972781 | pubmed:pagination | 3988-93 | lld:pubmed |
pubmed-article:2972781 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
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pubmed-article:2972781 | pubmed:year | 1988 | lld:pubmed |
pubmed-article:2972781 | pubmed:articleTitle | Pleiotropic effects of the Bcg gene. II. Genetic restriction of responses to mitogens and allogeneic targets. | lld:pubmed |
pubmed-article:2972781 | pubmed:affiliation | Département de Microbiologie et d'Immunologie, Université de Montréal, Québec, Canada. | lld:pubmed |
pubmed-article:2972781 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:2972781 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
pubmed-article:2972781 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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