| pubmed-article:2963410 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2963410 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:2963410 | lifeskim:mentions | umls-concept:C0024264 | lld:lifeskim |
| pubmed-article:2963410 | lifeskim:mentions | umls-concept:C0026249 | lld:lifeskim |
| pubmed-article:2963410 | lifeskim:mentions | umls-concept:C0039185 | lld:lifeskim |
| pubmed-article:2963410 | lifeskim:mentions | umls-concept:C0085732 | lld:lifeskim |
| pubmed-article:2963410 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:2963410 | lifeskim:mentions | umls-concept:C1533691 | lld:lifeskim |
| pubmed-article:2963410 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:2963410 | pubmed:dateCreated | 1988-3-24 | lld:pubmed |
| pubmed-article:2963410 | pubmed:abstractText | The effects of T-2 toxin on the in vitro mitogen responses and the antibody-producing ability of human peripheral blood lymphocytes were evaluated. T-2 toxin inhibited the mitogen response to concanavalin A (ConA) at a lower concentration (1.6 ng/ml) as compared to phytohemagglutinin (2.4 ng/ml) and pokeweed mitogen (2.4 ng/ml). Maximum inhibition was observed when the toxin was present during the first 8 h; however, the cultures were not refractory to inhibition until 48 h after culture initiation. The antibody-producing ability was inhibited by T-2 toxin concentrations of greater than or equal to 3.2 ng/ml. T-2 toxin did not induce or interfere with the generation of suppressor cells by ConA. The results of this study indicate that various lymphocyte subpopulations have different susceptibilities to T-2 toxin. The activation process associated with lymphocyte proliferation appears to be one of the most sensitive time periods. | lld:pubmed |
| pubmed-article:2963410 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2963410 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2963410 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2963410 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2963410 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2963410 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2963410 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2963410 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2963410 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:2963410 | pubmed:issn | 0378-4274 | lld:pubmed |
| pubmed-article:2963410 | pubmed:author | pubmed-author:BlakleyB RBR | lld:pubmed |
| pubmed-article:2963410 | pubmed:author | pubmed-author:TomarR SRS | lld:pubmed |
| pubmed-article:2963410 | pubmed:author | pubmed-author:De CoteauW... | lld:pubmed |
| pubmed-article:2963410 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2963410 | pubmed:volume | 40 | lld:pubmed |
| pubmed-article:2963410 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2963410 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2963410 | pubmed:pagination | 109-17 | lld:pubmed |
| pubmed-article:2963410 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:2963410 | pubmed:meshHeading | pubmed-meshheading:2963410-... | lld:pubmed |
| pubmed-article:2963410 | pubmed:meshHeading | pubmed-meshheading:2963410-... | lld:pubmed |
| pubmed-article:2963410 | pubmed:meshHeading | pubmed-meshheading:2963410-... | lld:pubmed |
| pubmed-article:2963410 | pubmed:meshHeading | pubmed-meshheading:2963410-... | lld:pubmed |
| pubmed-article:2963410 | pubmed:meshHeading | pubmed-meshheading:2963410-... | lld:pubmed |
| pubmed-article:2963410 | pubmed:meshHeading | pubmed-meshheading:2963410-... | lld:pubmed |
| pubmed-article:2963410 | pubmed:meshHeading | pubmed-meshheading:2963410-... | lld:pubmed |
| pubmed-article:2963410 | pubmed:meshHeading | pubmed-meshheading:2963410-... | lld:pubmed |
| pubmed-article:2963410 | pubmed:meshHeading | pubmed-meshheading:2963410-... | lld:pubmed |
| pubmed-article:2963410 | pubmed:meshHeading | pubmed-meshheading:2963410-... | lld:pubmed |
| pubmed-article:2963410 | pubmed:year | 1988 | lld:pubmed |
| pubmed-article:2963410 | pubmed:articleTitle | In vitro effects of T-2 toxin on the mitogen responsiveness and antibody-producing ability of human lymphocytes. | lld:pubmed |
| pubmed-article:2963410 | pubmed:affiliation | Department of Veterinary Physiological Sciences, University of Saskatchewan, Saskatoon, Canada. | lld:pubmed |
| pubmed-article:2963410 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2963410 | pubmed:publicationType | In Vitro | lld:pubmed |
| pubmed-article:2963410 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2963410 | lld:pubmed |
