| pubmed-article:2956989 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2956989 | lifeskim:mentions | umls-concept:C0226890 | lld:lifeskim |
| pubmed-article:2956989 | lifeskim:mentions | umls-concept:C0007603 | lld:lifeskim |
| pubmed-article:2956989 | lifeskim:mentions | umls-concept:C0086045 | lld:lifeskim |
| pubmed-article:2956989 | lifeskim:mentions | umls-concept:C0005528 | lld:lifeskim |
| pubmed-article:2956989 | lifeskim:mentions | umls-concept:C0178719 | lld:lifeskim |
| pubmed-article:2956989 | lifeskim:mentions | umls-concept:C0596235 | lld:lifeskim |
| pubmed-article:2956989 | lifeskim:mentions | umls-concept:C1698986 | lld:lifeskim |
| pubmed-article:2956989 | lifeskim:mentions | umls-concept:C0439282 | lld:lifeskim |
| pubmed-article:2956989 | lifeskim:mentions | umls-concept:C2347546 | lld:lifeskim |
| pubmed-article:2956989 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:2956989 | pubmed:dateCreated | 1987-10-5 | lld:pubmed |
| pubmed-article:2956989 | pubmed:abstractText | The interactions of Cd2+ with active Ca2+ transport systems in rat intestinal epithelial cells have been investigated. ATP-driven Ca2+ transport in basolateral plasma membrane vesicles was inhibited by Cd2+ with an I50 value of 1.6 nM free Cd2+ at 1 microM free Ca2+, using EGTA and HEEDTA to buffer Ca2+ and Cd2+ concentrations, respectively. The inhibition was competitive in nature since the Km value of Ca2+ increased with increasing Cd2+ concentrations while the Vmax remained constant. Cd2+ had similar effects on ATP-dependent Ca2+ uptake by permeabilized enterocytes, indicating that non-mitochondrial and mitochondrial Ca2+ stores are also inhibited by nanomolar concentrations of Cd2+. We conclude that ATP-driven Ca2+ transport systems are the most sensitive elements so far reported in Cd2+ intoxication. | lld:pubmed |
| pubmed-article:2956989 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2956989 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2956989 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2956989 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2956989 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2956989 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2956989 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2956989 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:2956989 | pubmed:issn | 0006-3002 | lld:pubmed |
| pubmed-article:2956989 | pubmed:author | pubmed-author:van OsC HCH | lld:pubmed |
| pubmed-article:2956989 | pubmed:author | pubmed-author:VerbostP MPM | lld:pubmed |
| pubmed-article:2956989 | pubmed:author | pubmed-author:SendenM HMH | lld:pubmed |
| pubmed-article:2956989 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2956989 | pubmed:day | 20 | lld:pubmed |
| pubmed-article:2956989 | pubmed:volume | 902 | lld:pubmed |
| pubmed-article:2956989 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2956989 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2956989 | pubmed:pagination | 247-52 | lld:pubmed |
| pubmed-article:2956989 | pubmed:dateRevised | 2010-11-18 | lld:pubmed |
| pubmed-article:2956989 | pubmed:meshHeading | pubmed-meshheading:2956989-... | lld:pubmed |
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| pubmed-article:2956989 | pubmed:meshHeading | pubmed-meshheading:2956989-... | lld:pubmed |
| pubmed-article:2956989 | pubmed:meshHeading | pubmed-meshheading:2956989-... | lld:pubmed |
| pubmed-article:2956989 | pubmed:meshHeading | pubmed-meshheading:2956989-... | lld:pubmed |
| pubmed-article:2956989 | pubmed:meshHeading | pubmed-meshheading:2956989-... | lld:pubmed |
| pubmed-article:2956989 | pubmed:meshHeading | pubmed-meshheading:2956989-... | lld:pubmed |
| pubmed-article:2956989 | pubmed:meshHeading | pubmed-meshheading:2956989-... | lld:pubmed |
| pubmed-article:2956989 | pubmed:year | 1987 | lld:pubmed |
| pubmed-article:2956989 | pubmed:articleTitle | Nanomolar concentrations of Cd2+ inhibit Ca2+ transport systems in plasma membranes and intracellular Ca2+ stores in intestinal epithelium. | lld:pubmed |
| pubmed-article:2956989 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2956989 | pubmed:publicationType | In Vitro | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2956989 | lld:pubmed |
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| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2956989 | lld:pubmed |
