| pubmed-article:2944757 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2944757 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:2944757 | lifeskim:mentions | umls-concept:C0014563 | lld:lifeskim |
| pubmed-article:2944757 | lifeskim:mentions | umls-concept:C0032176 | lld:lifeskim |
| pubmed-article:2944757 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:2944757 | lifeskim:mentions | umls-concept:C1854187 | lld:lifeskim |
| pubmed-article:2944757 | lifeskim:mentions | umls-concept:C0032172 | lld:lifeskim |
| pubmed-article:2944757 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
| pubmed-article:2944757 | lifeskim:mentions | umls-concept:C1548982 | lld:lifeskim |
| pubmed-article:2944757 | lifeskim:mentions | umls-concept:C0283766 | lld:lifeskim |
| pubmed-article:2944757 | pubmed:issue | 1-2 | lld:pubmed |
| pubmed-article:2944757 | pubmed:dateCreated | 1986-11-17 | lld:pubmed |
| pubmed-article:2944757 | pubmed:abstractText | The effect of AD6 (8-monochloro-3-beta-diethylamino-ethyl-4-methyl-7- ethoxycarbonylmethoxycoumarin) was studied in vitro on washed human platelet aggregation and beta-thromboglobulin (beta TG) release induced by PAF alone or in combination with epinephrine. AD6 caused concentration-dependent inhibition of aggregation and beta TG release. Acetylsalicylic acid and the ADP scavenger apyrase were ineffective on the same parameters, while the specific PAF antagonist CV 3988, the Ca2+ antagonist diltiazem and the cyclo-oxygenase-lipoxygenase inhibitors nordihydroguaiaretic acid and BW 755C inhibited aggregation. The results indicate that AD6 is an inhibitor of platelet aggregation in vitro with a mode of action different from cyclo-oxygenase blockade. | lld:pubmed |
| pubmed-article:2944757 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2944757 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2944757 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2944757 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2944757 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2944757 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2944757 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2944757 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2944757 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2944757 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2944757 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2944757 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2944757 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2944757 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2944757 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:2944757 | pubmed:issn | 0014-2999 | lld:pubmed |
| pubmed-article:2944757 | pubmed:author | pubmed-author:DejanaEE | lld:pubmed |
| pubmed-article:2944757 | pubmed:author | pubmed-author:ProsdocimiMM | lld:pubmed |
| pubmed-article:2944757 | pubmed:author | pubmed-author:ZanettiAA | lld:pubmed |
| pubmed-article:2944757 | pubmed:author | pubmed-author:ZattaAA | lld:pubmed |
| pubmed-article:2944757 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2944757 | pubmed:day | 22 | lld:pubmed |
| pubmed-article:2944757 | pubmed:volume | 128 | lld:pubmed |
| pubmed-article:2944757 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2944757 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2944757 | pubmed:pagination | 119-27 | lld:pubmed |
| pubmed-article:2944757 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:2944757 | pubmed:meshHeading | pubmed-meshheading:2944757-... | lld:pubmed |
| pubmed-article:2944757 | pubmed:meshHeading | pubmed-meshheading:2944757-... | lld:pubmed |
| pubmed-article:2944757 | pubmed:meshHeading | pubmed-meshheading:2944757-... | lld:pubmed |
| pubmed-article:2944757 | pubmed:meshHeading | pubmed-meshheading:2944757-... | lld:pubmed |
| pubmed-article:2944757 | pubmed:meshHeading | pubmed-meshheading:2944757-... | lld:pubmed |
| pubmed-article:2944757 | pubmed:meshHeading | pubmed-meshheading:2944757-... | lld:pubmed |
| pubmed-article:2944757 | pubmed:meshHeading | pubmed-meshheading:2944757-... | lld:pubmed |
| pubmed-article:2944757 | pubmed:meshHeading | pubmed-meshheading:2944757-... | lld:pubmed |
| pubmed-article:2944757 | pubmed:meshHeading | pubmed-meshheading:2944757-... | lld:pubmed |
| pubmed-article:2944757 | pubmed:meshHeading | pubmed-meshheading:2944757-... | lld:pubmed |
| pubmed-article:2944757 | pubmed:meshHeading | pubmed-meshheading:2944757-... | lld:pubmed |
| pubmed-article:2944757 | pubmed:meshHeading | pubmed-meshheading:2944757-... | lld:pubmed |
| pubmed-article:2944757 | pubmed:meshHeading | pubmed-meshheading:2944757-... | lld:pubmed |
| pubmed-article:2944757 | pubmed:year | 1986 | lld:pubmed |
| pubmed-article:2944757 | pubmed:articleTitle | The effect of AD6 (8-monochloro-3-beta-diethylamino-ethyl-4-methyl-7-ethoxy- carbonylmethoxycoumarin) on washed human platelet aggregation induced by platelet activating factor (PAF) and epinephrine. | lld:pubmed |
| pubmed-article:2944757 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2944757 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:2944757 | pubmed:publicationType | In Vitro | lld:pubmed |
| pubmed-article:2944757 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
