pubmed-article:2943999 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:2943999 | lifeskim:mentions | umls-concept:C0001675 | lld:lifeskim |
pubmed-article:2943999 | lifeskim:mentions | umls-concept:C0039194 | lld:lifeskim |
pubmed-article:2943999 | lifeskim:mentions | umls-concept:C0521457 | lld:lifeskim |
pubmed-article:2943999 | lifeskim:mentions | umls-concept:C0017337 | lld:lifeskim |
pubmed-article:2943999 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
pubmed-article:2943999 | lifeskim:mentions | umls-concept:C1823153 | lld:lifeskim |
pubmed-article:2943999 | lifeskim:mentions | umls-concept:C2349976 | lld:lifeskim |
pubmed-article:2943999 | lifeskim:mentions | umls-concept:C1552644 | lld:lifeskim |
pubmed-article:2943999 | lifeskim:mentions | umls-concept:C1880371 | lld:lifeskim |
pubmed-article:2943999 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
pubmed-article:2943999 | lifeskim:mentions | umls-concept:C0591833 | lld:lifeskim |
pubmed-article:2943999 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
pubmed-article:2943999 | pubmed:issue | 6082 | lld:pubmed |
pubmed-article:2943999 | pubmed:dateCreated | 1986-10-8 | lld:pubmed |
pubmed-article:2943999 | pubmed:abstractText | The search for the genes encoding the T-cell receptor alpha and chains revealed a third gene, T gamma (ref. 1), which shares with t T alpha (refs 2-7) and T beta (refs 8-15) genes a number of structure features, including somatic rearrangement during T-cell development. T gamma gene expression appears to be unnecessary in son mature T cells and is at its greatest in fetal thymocytes encouraging speculation that T gamma has a role in T-cell development and may be involved in the recognition of polymorphic major histocompatibility complex (MHC) products during thymic education. One argument against the participation of T gamma in such a process has been its apparently limited diversity, due to the small number of gene segments available for rearrangement. We here describe the identification of additional T gamma V-gene segments and demonstrate that they can be rearranged to previously identified J- and C-gene segments and are expressed in fetal thymocytes. In addition we describe a variety of patterns of T gamma mRNA processing which may be significant for T gamma gene regulation. | lld:pubmed |
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pubmed-article:2943999 | pubmed:language | eng | lld:pubmed |
pubmed-article:2943999 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2943999 | pubmed:citationSubset | IM | lld:pubmed |
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pubmed-article:2943999 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:2943999 | pubmed:issn | 0028-0836 | lld:pubmed |
pubmed-article:2943999 | pubmed:author | pubmed-author:TonegawaSS | lld:pubmed |
pubmed-article:2943999 | pubmed:author | pubmed-author:HeiligJ SJS | lld:pubmed |
pubmed-article:2943999 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:2943999 | pubmed:volume | 322 | lld:pubmed |
pubmed-article:2943999 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:2943999 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:2943999 | pubmed:pagination | 836-40 | lld:pubmed |
pubmed-article:2943999 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
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pubmed-article:2943999 | pubmed:articleTitle | Diversity of murine gamma genes and expression in fetal and adult T lymphocytes. | lld:pubmed |
pubmed-article:2943999 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:2943999 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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