pubmed-article:2938969 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:2938969 | lifeskim:mentions | umls-concept:C0035820 | lld:lifeskim |
pubmed-article:2938969 | lifeskim:mentions | umls-concept:C0024264 | lld:lifeskim |
pubmed-article:2938969 | lifeskim:mentions | umls-concept:C0003320 | lld:lifeskim |
pubmed-article:2938969 | lifeskim:mentions | umls-concept:C1704632 | lld:lifeskim |
pubmed-article:2938969 | lifeskim:mentions | umls-concept:C0871261 | lld:lifeskim |
pubmed-article:2938969 | lifeskim:mentions | umls-concept:C2911692 | lld:lifeskim |
pubmed-article:2938969 | lifeskim:mentions | umls-concept:C1706817 | lld:lifeskim |
pubmed-article:2938969 | lifeskim:mentions | umls-concept:C0205430 | lld:lifeskim |
pubmed-article:2938969 | lifeskim:mentions | umls-concept:C0591833 | lld:lifeskim |
pubmed-article:2938969 | pubmed:issue | 4 | lld:pubmed |
pubmed-article:2938969 | pubmed:dateCreated | 1986-6-11 | lld:pubmed |
pubmed-article:2938969 | pubmed:abstractText | Mouse splenic macrophages (M phi) were tested for their ability to potentiate in vitro allogeneic mixed lymphocyte response (MLR) of highly purified syngeneic responder T cells against allogeneic M phi. It was shown that even extremely low numbers of M phi syngeneic to the responder T cells were able to induce significantly stronger MLR. This potentiating effect was demonstrated to be expressed via the self-Ia antigens present on the surface of syngeneic M phi. The functional involvement of self-Ia antigens was substantiated by two approaches: (a) by using monoclonal antibodies specific for I-region determinants of the responder haplotype M phi and (b) by setting up MLR cultures with stimulator M phi of (responder X stimulator) F1 origin which express both self- and allo-Ia antigens. The results obtained in this study demonstrate that the presentation of self-Ia antigens, in conjunction with the recognition of allo-major histocompatibility complex antigens, are required for in vitro primary MLR. | lld:pubmed |
pubmed-article:2938969 | pubmed:language | eng | lld:pubmed |
pubmed-article:2938969 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2938969 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:2938969 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2938969 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2938969 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2938969 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2938969 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:2938969 | pubmed:month | Apr | lld:pubmed |
pubmed-article:2938969 | pubmed:issn | 0014-2980 | lld:pubmed |
pubmed-article:2938969 | pubmed:author | pubmed-author:PapamichailMM | lld:pubmed |
pubmed-article:2938969 | pubmed:author | pubmed-author:BaxevanisC... | lld:pubmed |
pubmed-article:2938969 | pubmed:author | pubmed-author:IoannidesC... | lld:pubmed |
pubmed-article:2938969 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:2938969 | pubmed:volume | 16 | lld:pubmed |
pubmed-article:2938969 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:2938969 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:2938969 | pubmed:pagination | 361-5 | lld:pubmed |
pubmed-article:2938969 | pubmed:dateRevised | 2003-11-14 | lld:pubmed |
pubmed-article:2938969 | pubmed:meshHeading | pubmed-meshheading:2938969-... | lld:pubmed |
pubmed-article:2938969 | pubmed:meshHeading | pubmed-meshheading:2938969-... | lld:pubmed |
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pubmed-article:2938969 | pubmed:meshHeading | pubmed-meshheading:2938969-... | lld:pubmed |
pubmed-article:2938969 | pubmed:year | 1986 | lld:pubmed |
pubmed-article:2938969 | pubmed:articleTitle | The role of self-Ia antigens in the murine mixed lymphocyte response. | lld:pubmed |
pubmed-article:2938969 | pubmed:publicationType | Journal Article | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2938969 | lld:pubmed |