| pubmed-article:293728 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:293728 | lifeskim:mentions | umls-concept:C0007635 | lld:lifeskim |
| pubmed-article:293728 | lifeskim:mentions | umls-concept:C0598180 | lld:lifeskim |
| pubmed-article:293728 | lifeskim:mentions | umls-concept:C0332197 | lld:lifeskim |
| pubmed-article:293728 | lifeskim:mentions | umls-concept:C0205148 | lld:lifeskim |
| pubmed-article:293728 | lifeskim:mentions | umls-concept:C1704241 | lld:lifeskim |
| pubmed-article:293728 | pubmed:issue | 12 | lld:pubmed |
| pubmed-article:293728 | pubmed:dateCreated | 1980-3-27 | lld:pubmed |
| pubmed-article:293728 | pubmed:abstractText | Monolayer cultures of normal or transformed fibroblasts and of liver cells fixed in a glutaraldehyde solution containing 300 microM filipin, a sterol-specific polyene antibiotic, were freeze-fractured to study the distribution of cholesterol within their plasma membranes. Filipin-sterol complexes, recognizable as 25- to 30-nm protuberances scattered in the fracture face of plasma membrane, were absent from invaginations corresponding to large, bristle-coated pits (and possibly also from small, flask-shaped invaginations). These results suggest that invaginating regions on the cell surface are specialized plasma membrane domains with a lower cholesterol content than the surrounding membrane. The localized change in membrane fluidity due to the low cholesterol concentration could play a role in endocytosis. | lld:pubmed |
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| pubmed-article:293728 | pubmed:language | eng | lld:pubmed |
| pubmed-article:293728 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:293728 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:293728 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:293728 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:293728 | pubmed:issn | 0027-8424 | lld:pubmed |
| pubmed-article:293728 | pubmed:author | pubmed-author:VassalliPP | lld:pubmed |
| pubmed-article:293728 | pubmed:author | pubmed-author:MontesanoRR | lld:pubmed |
| pubmed-article:293728 | pubmed:author | pubmed-author:OrciLL | lld:pubmed |
| pubmed-article:293728 | pubmed:author | pubmed-author:PerreletAA | lld:pubmed |
| pubmed-article:293728 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:293728 | pubmed:volume | 76 | lld:pubmed |
| pubmed-article:293728 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:293728 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:293728 | pubmed:pagination | 6391-5 | lld:pubmed |
| pubmed-article:293728 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:293728 | pubmed:year | 1979 | lld:pubmed |
| pubmed-article:293728 | pubmed:articleTitle | Absence of filipin-sterol complexes from large coated pits on the surface of culture cells. | lld:pubmed |
| pubmed-article:293728 | pubmed:publicationType | Journal Article | lld:pubmed |
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