pubmed-article:2907038 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:2907038 | lifeskim:mentions | umls-concept:C0441655 | lld:lifeskim |
pubmed-article:2907038 | lifeskim:mentions | umls-concept:C0003360 | lld:lifeskim |
pubmed-article:2907038 | lifeskim:mentions | umls-concept:C0008931 | lld:lifeskim |
pubmed-article:2907038 | lifeskim:mentions | umls-concept:C1707455 | lld:lifeskim |
pubmed-article:2907038 | lifeskim:mentions | umls-concept:C0242896 | lld:lifeskim |
pubmed-article:2907038 | lifeskim:mentions | umls-concept:C0065972 | lld:lifeskim |
pubmed-article:2907038 | pubmed:issue | 9 | lld:pubmed |
pubmed-article:2907038 | pubmed:dateCreated | 1989-4-26 | lld:pubmed |
pubmed-article:2907038 | pubmed:abstractText | The antihistamine and anticholinergic properties of mequitazine have been investigated and compared with those of clemizole. Both mequitazine and clemizole antagonized the effect of histamine in guinea-pig ileum competitively, the pA2 values calculated by Schild plot were 9.95 +/- 0.44 for mequitazine and 10.54 +/- 0.44 for clemizole. Mequitazine at 10(-7) M produced a parallel shift of the dose-response curve to acetylcholine in the rat duodenum, clemizole and the lower doses of mequitazine failed to modify the effect of acetylcholine. The potency of mequitazine and clemizole as H1-histamine blockers is similar, but only mequitazine at highest concentration used showed anticholinergic activity. | lld:pubmed |
pubmed-article:2907038 | pubmed:language | eng | lld:pubmed |
pubmed-article:2907038 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2907038 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:2907038 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2907038 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2907038 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2907038 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2907038 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2907038 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2907038 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2907038 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:2907038 | pubmed:month | Sep | lld:pubmed |
pubmed-article:2907038 | pubmed:issn | 0022-3573 | lld:pubmed |
pubmed-article:2907038 | pubmed:author | pubmed-author:Morales-Oliva... | lld:pubmed |
pubmed-article:2907038 | pubmed:author | pubmed-author:RubinDD | lld:pubmed |
pubmed-article:2907038 | pubmed:author | pubmed-author:EstesNN | lld:pubmed |
pubmed-article:2907038 | pubmed:author | pubmed-author:Martinez-MirI... | lld:pubmed |
pubmed-article:2907038 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:2907038 | pubmed:volume | 40 | lld:pubmed |
pubmed-article:2907038 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:2907038 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:2907038 | pubmed:pagination | 655-6 | lld:pubmed |
pubmed-article:2907038 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
pubmed-article:2907038 | pubmed:meshHeading | pubmed-meshheading:2907038-... | lld:pubmed |
pubmed-article:2907038 | pubmed:meshHeading | pubmed-meshheading:2907038-... | lld:pubmed |
pubmed-article:2907038 | pubmed:meshHeading | pubmed-meshheading:2907038-... | lld:pubmed |
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pubmed-article:2907038 | pubmed:meshHeading | pubmed-meshheading:2907038-... | lld:pubmed |
pubmed-article:2907038 | pubmed:meshHeading | pubmed-meshheading:2907038-... | lld:pubmed |
pubmed-article:2907038 | pubmed:meshHeading | pubmed-meshheading:2907038-... | lld:pubmed |
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pubmed-article:2907038 | pubmed:meshHeading | pubmed-meshheading:2907038-... | lld:pubmed |
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pubmed-article:2907038 | pubmed:meshHeading | pubmed-meshheading:2907038-... | lld:pubmed |
pubmed-article:2907038 | pubmed:year | 1988 | lld:pubmed |
pubmed-article:2907038 | pubmed:articleTitle | Antihistaminic and anticholinergic activities of mequitazine in comparison with clemizole. | lld:pubmed |
pubmed-article:2907038 | pubmed:affiliation | Department de Farmacologia i Farmacotecnia, Universitat de Valencia, Facultat de Medicina, Spain. | lld:pubmed |
pubmed-article:2907038 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:2907038 | pubmed:publicationType | Comparative Study | lld:pubmed |
pubmed-article:2907038 | pubmed:publicationType | In Vitro | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2907038 | lld:pubmed |