| pubmed-article:2904398 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2904398 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:2904398 | lifeskim:mentions | umls-concept:C0311400 | lld:lifeskim |
| pubmed-article:2904398 | lifeskim:mentions | umls-concept:C2265833 | lld:lifeskim |
| pubmed-article:2904398 | lifeskim:mentions | umls-concept:C0332206 | lld:lifeskim |
| pubmed-article:2904398 | pubmed:issue | 9 | lld:pubmed |
| pubmed-article:2904398 | pubmed:dateCreated | 1989-1-13 | lld:pubmed |
| pubmed-article:2904398 | pubmed:abstractText | The purpose of this study was to further document the role of locally released norepinephrine (NE) in the control of metabolic and endocrine responses to exercise in rats. Post-ganglionic blockade with bretylium (20 mg.kg-1, i.v.) reduced NE release from sympathetic nerve endings and triggered a compensatory increase in epinephrine (E) release from the adrenal medulla, as reflected by plasma NE and E concentrations at rest and exercise (E/NE ratio = 2.92 +/- 0.53 and 2.48 +/- 0.51 vs 0.62 +/- 0.15 and 1.48 +/- 0.18 in control rats; mean +/- SE). Following bretylium administration a reduction in running time to exhaustion (28 m.min-1, 8% slope: 33 +/- 2 min vs 74 +/- 10 min) was associated with 1) a faster decrease in blood glucose concentration (3.58 +/- 0.80 mM vs 8.09 +/- 0.38 mM in control rats exercised for 33 min); and 2) an increased glycogen store utilization in fast-twitch muscles (superficial vastus lateralis and gastrocnemius lateralis). Glycogen utilization was not modified in soleus muscle and in the liver. Taken together these results suggest that post-ganglionic blockade increased carbohydrate store and peripheral blood glucose utilization. This could reflect an impairment in fat mobilization and utilization which might be secondary to a reduction of NE release in the adipose tissue and/or in the endocrine pancreas. | lld:pubmed |
| pubmed-article:2904398 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2904398 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2904398 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2904398 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2904398 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2904398 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2904398 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2904398 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2904398 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2904398 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2904398 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2904398 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:2904398 | pubmed:issn | 0018-5043 | lld:pubmed |
| pubmed-article:2904398 | pubmed:author | pubmed-author:BrissonGG | lld:pubmed |
| pubmed-article:2904398 | pubmed:author | pubmed-author:PéronnetFF | lld:pubmed |
| pubmed-article:2904398 | pubmed:author | pubmed-author:BéliveauLL | lld:pubmed |
| pubmed-article:2904398 | pubmed:author | pubmed-author:TrudeauFF | lld:pubmed |
| pubmed-article:2904398 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2904398 | pubmed:volume | 20 | lld:pubmed |
| pubmed-article:2904398 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2904398 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2904398 | pubmed:pagination | 546-50 | lld:pubmed |
| pubmed-article:2904398 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
| pubmed-article:2904398 | pubmed:meshHeading | pubmed-meshheading:2904398-... | lld:pubmed |
| pubmed-article:2904398 | pubmed:meshHeading | pubmed-meshheading:2904398-... | lld:pubmed |
| pubmed-article:2904398 | pubmed:meshHeading | pubmed-meshheading:2904398-... | lld:pubmed |
| pubmed-article:2904398 | pubmed:meshHeading | pubmed-meshheading:2904398-... | lld:pubmed |
| pubmed-article:2904398 | pubmed:meshHeading | pubmed-meshheading:2904398-... | lld:pubmed |
| pubmed-article:2904398 | pubmed:meshHeading | pubmed-meshheading:2904398-... | lld:pubmed |
| pubmed-article:2904398 | pubmed:meshHeading | pubmed-meshheading:2904398-... | lld:pubmed |
| pubmed-article:2904398 | pubmed:meshHeading | pubmed-meshheading:2904398-... | lld:pubmed |
| pubmed-article:2904398 | pubmed:meshHeading | pubmed-meshheading:2904398-... | lld:pubmed |
| pubmed-article:2904398 | pubmed:meshHeading | pubmed-meshheading:2904398-... | lld:pubmed |
| pubmed-article:2904398 | pubmed:meshHeading | pubmed-meshheading:2904398-... | lld:pubmed |
| pubmed-article:2904398 | pubmed:meshHeading | pubmed-meshheading:2904398-... | lld:pubmed |
| pubmed-article:2904398 | pubmed:year | 1988 | lld:pubmed |
| pubmed-article:2904398 | pubmed:articleTitle | Sympatho-endocrine and metabolic responses to exercise under post-ganglionic blockade in rats. | lld:pubmed |
| pubmed-article:2904398 | pubmed:affiliation | Département d'éducation physique, Université de Montréal, Canada. | lld:pubmed |
| pubmed-article:2904398 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2904398 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
