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pubmed-article:2895621pubmed:abstractTextThe use of somatostatin in the treatment of a newborn infant with hyperinsulinism is reported. When administered alone, somatostatin was only able to prevent hypoglycemia for a short period of time, whereas the addition of a constant infusion of glucagon allowed successful control of the patient's hypoglycemia. As hyperinsulinism relapsed after a subtotal pancreatectomy, a trial was carried out with a somatostatin analog, which has an expected longer duration of action. It led to a significant rise in the blood glucose level but failed to prevent safely hypoglycemia even when 4 injections were performed daily.lld:pubmed
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pubmed-article:2895621pubmed:authorpubmed-author:DyonJ FJFlld:pubmed
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pubmed-article:2895621pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:2895621pubmed:year1987lld:pubmed
pubmed-article:2895621pubmed:articleTitle[Somatostatin in a case of neonatal hyperinsulinism caused by focal adenomatosis of the head of pancreas].lld:pubmed
pubmed-article:2895621pubmed:affiliationService de Médecine Néonatale et Réanimation Infantile, C.H.U. de Grenoble.lld:pubmed
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