pubmed-article:2893593 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:2893593 | lifeskim:mentions | umls-concept:C0021843 | lld:lifeskim |
pubmed-article:2893593 | lifeskim:mentions | umls-concept:C0037659 | lld:lifeskim |
pubmed-article:2893593 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
pubmed-article:2893593 | lifeskim:mentions | umls-concept:C1517004 | lld:lifeskim |
pubmed-article:2893593 | pubmed:issue | 2 | lld:pubmed |
pubmed-article:2893593 | pubmed:dateCreated | 1988-3-7 | lld:pubmed |
pubmed-article:2893593 | pubmed:abstractText | The effect of somatostatin (SS-14) was tested in an anesthetized rabbit model of closed-loop ileal obstruction. Experimental groups included (1) immediate treatment (N = 6) receiving SS-14 2,000 pmol X kg-1 X h-1 intravenously (I.V.) beginning at the time of ileal obstruction, (2) delayed treatment (N = 5) receiving SS-14 beginning 6 hours following ileal obstruction, and (3) control (N = 6) receiving only hydration. After 24 hours, all rabbits were killed. Significantly decreased intestinal luminal volume and sodium and potassium output was observed with both immediate and delayed SS-14 treatment when compared to control. Additionally, the gross and microscopic pathologic features of intestinal distension, inflammation, and necrosis seen in control rabbits were absent in rabbits treated with SS-14. The known broad spectrum of physiologic activity of SS-14 on the gastrointestinal tract appeared beneficial in this rabbit model of intestinal obstruction. | lld:pubmed |
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pubmed-article:2893593 | pubmed:language | eng | lld:pubmed |
pubmed-article:2893593 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2893593 | pubmed:citationSubset | AIM | lld:pubmed |
pubmed-article:2893593 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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pubmed-article:2893593 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:2893593 | pubmed:month | Feb | lld:pubmed |
pubmed-article:2893593 | pubmed:issn | 0003-4932 | lld:pubmed |
pubmed-article:2893593 | pubmed:author | pubmed-author:DebasH THT | lld:pubmed |
pubmed-article:2893593 | pubmed:author | pubmed-author:FonkalsrudE... | lld:pubmed |
pubmed-article:2893593 | pubmed:author | pubmed-author:MulvihillS... | lld:pubmed |
pubmed-article:2893593 | pubmed:author | pubmed-author:PappasT NTN | lld:pubmed |
pubmed-article:2893593 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:2893593 | pubmed:volume | 207 | lld:pubmed |
pubmed-article:2893593 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:2893593 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:2893593 | pubmed:pagination | 169-73 | lld:pubmed |
pubmed-article:2893593 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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pubmed-article:2893593 | pubmed:meshHeading | pubmed-meshheading:2893593-... | lld:pubmed |
pubmed-article:2893593 | pubmed:year | 1988 | lld:pubmed |
pubmed-article:2893593 | pubmed:articleTitle | The effect of somatostatin on experimental intestinal obstruction. | lld:pubmed |
pubmed-article:2893593 | pubmed:affiliation | Department of Surgery, University of California, San Francisco 94143-0104. | lld:pubmed |
pubmed-article:2893593 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:2893593 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
pubmed-article:2893593 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
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