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pubmed-article:2893257pubmed:abstractTextClone pPF11.1 encodes a Plasmodium falciparum antigen expressed during the intraerythrocytic cycle and containing tandem repeats of a 9 amino acid unit. We report here an analysis of the genomic region specific for 11.1, which extends over 30 kb. It contains two blocks of repeats, spanning 13 kb and 9 kb. The restriction map suggests that the locus may result from a gene duplication. The 11.1 region is present in all P. falciparum strains examined so far. Southern analysis of 8 distinct isolates indicates that the locus is highly polymorphic. Thus the pPF11.1 repeats constitute a sensitive and discriminating probe to type P. falciparum strains.lld:pubmed
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pubmed-article:2893257pubmed:articleTitleThe polymorphic 11.1 locus of Plasmodium falciparum.lld:pubmed
pubmed-article:2893257pubmed:affiliationUnité de Parasitologie Expérimentale, Institut Pasteur, Paris, France.lld:pubmed
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