| pubmed-article:2891861 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2891861 | lifeskim:mentions | umls-concept:C0318809 | lld:lifeskim |
| pubmed-article:2891861 | lifeskim:mentions | umls-concept:C0042333 | lld:lifeskim |
| pubmed-article:2891861 | lifeskim:mentions | umls-concept:C0370215 | lld:lifeskim |
| pubmed-article:2891861 | lifeskim:mentions | umls-concept:C0598394 | lld:lifeskim |
| pubmed-article:2891861 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:2891861 | pubmed:dateCreated | 1988-2-20 | lld:pubmed |
| pubmed-article:2891861 | pubmed:abstractText | The RNA genomes of 43 vesicular stomatitis virus (VSV) isolates of the New Jersey (NJ) serotype were T1-ribonuclease fingerprinted to compare the extent of genetic diversity of virus from regions of epizootic and enzootic disease activity. Forty of these viruses were obtained from Central America during 1982 to 1985. The other three were older isolates, including a 1970 isolate from Culex nigripalpus mosquitos in Guatemala, a 1960 bovine isolate from Panama, and a 1976 isolate from mosquitos (Mansonia indubitans) in Ecuador. The data indicate that extensive genetic diversity exists among virus isolates from this predominantly enzootic disease zone. Six distinct T1 fingerprint groups were identified for the Central American VSV NJ isolates from 1982 to 1985. The 1960 VSV NJ isolate from Panama and the 1976 isolate from Ecuador formed two additional distinct fingerprint groups. This finding is in sharp contrast to the relatively close genetic relationship existing among VSV NJ isolates obtained from predominantly epizootic disease areas of the United States and Mexico during the same period (S. T. Nichol, J. Virol. 61:1029-1036, 1987). In this previous study, RNA genome T1 fingerprint differences were observed among isolates from different epizootics; however, the isolates were all clearly members of one large T1 fingerprint group. The eight T1 fingerprint groups described here for Central American and Ecuadorian viruses are distinct from those characterized earlier for virus isolates from the United States and Mexico and for the common laboratory virus strains Ogden and Hazelhurst. Despite being isolated 14 years earlier, the 1970 insect isolate from Guatemala is clearly a member of one of the 1982 to 1985 Central American virus fingerprint groups. This indicates that although virus genetic diversity in the region is extensive, under certain natural conditions particular virus genotypes can be relatively stably maintained for an extended period. The implications of these findings for the evolution of VSV NJ and epizootiology of the disease are discussed. | lld:pubmed |
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| pubmed-article:2891861 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2891861 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2891861 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:2891861 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2891861 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:2891861 | pubmed:issn | 0022-538X | lld:pubmed |
| pubmed-article:2891861 | pubmed:author | pubmed-author:NicholS TST | lld:pubmed |
| pubmed-article:2891861 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2891861 | pubmed:volume | 62 | lld:pubmed |
| pubmed-article:2891861 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2891861 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2891861 | pubmed:pagination | 572-9 | lld:pubmed |
| pubmed-article:2891861 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:2891861 | pubmed:year | 1988 | lld:pubmed |
| pubmed-article:2891861 | pubmed:articleTitle | Genetic diversity of enzootic isolates of vesicular stomatitis virus New Jersey. | lld:pubmed |
| pubmed-article:2891861 | pubmed:affiliation | Cell and Molecular Biology Program, School of Veterinary Medicine, University of Nevada, Reno 89557. | lld:pubmed |
| pubmed-article:2891861 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2891861 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
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