| pubmed-article:2884193 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2884193 | lifeskim:mentions | umls-concept:C0011616 | lld:lifeskim |
| pubmed-article:2884193 | lifeskim:mentions | umls-concept:C0085979 | lld:lifeskim |
| pubmed-article:2884193 | lifeskim:mentions | umls-concept:C0079720 | lld:lifeskim |
| pubmed-article:2884193 | lifeskim:mentions | umls-concept:C0010583 | lld:lifeskim |
| pubmed-article:2884193 | lifeskim:mentions | umls-concept:C0001758 | lld:lifeskim |
| pubmed-article:2884193 | lifeskim:mentions | umls-concept:C1527148 | lld:lifeskim |
| pubmed-article:2884193 | lifeskim:mentions | umls-concept:C0392747 | lld:lifeskim |
| pubmed-article:2884193 | lifeskim:mentions | umls-concept:C0443172 | lld:lifeskim |
| pubmed-article:2884193 | lifeskim:mentions | umls-concept:C1304884 | lld:lifeskim |
| pubmed-article:2884193 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:2884193 | pubmed:dateCreated | 1987-7-20 | lld:pubmed |
| pubmed-article:2884193 | pubmed:abstractText | Changes in lymphocyte subpopulations were investigated in guinea pig lymph nodes during the development of contact sensitivity to 2,4-dinitrofluorobenzene (DNFB) and following the injection of cyclophosphamide (CY; 300 mg/kg) using a panel of monoclonal antibodies against guinea pig lymphocyte surface markers. Application of a sensitizing dose of DNFB to the ear resulted in a significant increase in the number of cells recovered from the draining auricular and cervical lymph nodes, 4 and 6 days post sensitization. A significant increase in the number of cells in the contralateral cervical node was found at day 6 but not at day 4. At 4 days postsensitization the proportions of Ia positive lymphocytes were higher than those of immunoglobulin positive B cells in the draining auricular and cervical node and the contralateral cervical lymph nodes suggesting T-cell "activation". Four and six days after sensitization there were no significant changes in the proportions of Pan T and T suppressor/cytotoxic (Ts/c) positive lymphocytes in the draining auricular and cervical lymph nodes. Although contact sensitivity is "classically" a T-cell mediated phenomenon there was a significant increase in the proportion of B cells found in the draining auricular node 4 days after sensitization as compared to the "normal" auricular node. 1, 2, 3 and 7 days after injection of CY there was a significant depletion in the proportion of B-lymphocytes in the cervical lymph node. This effect was maximal between 2 and 3 days after CY and was paralleled by an increase in the proportion of Pan T positive cells.(ABSTRACT TRUNCATED AT 250 WORDS) | lld:pubmed |
| pubmed-article:2884193 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2884193 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2884193 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2884193 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2884193 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2884193 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2884193 | pubmed:issn | 0192-0561 | lld:pubmed |
| pubmed-article:2884193 | pubmed:author | pubmed-author:TurkJ LJL | lld:pubmed |
| pubmed-article:2884193 | pubmed:author | pubmed-author:ScheperR JRJ | lld:pubmed |
| pubmed-article:2884193 | pubmed:author | pubmed-author:BakerDD | lld:pubmed |
| pubmed-article:2884193 | pubmed:author | pubmed-author:TaoB SBS | lld:pubmed |
| pubmed-article:2884193 | pubmed:author | pubmed-author:AntoniouA VAV | lld:pubmed |
| pubmed-article:2884193 | pubmed:author | pubmed-author:KarcherKK | lld:pubmed |
| pubmed-article:2884193 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2884193 | pubmed:volume | 9 | lld:pubmed |
| pubmed-article:2884193 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2884193 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2884193 | pubmed:pagination | 175-83 | lld:pubmed |
| pubmed-article:2884193 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:2884193 | pubmed:meshHeading | pubmed-meshheading:2884193-... | lld:pubmed |
| pubmed-article:2884193 | pubmed:meshHeading | pubmed-meshheading:2884193-... | lld:pubmed |
| pubmed-article:2884193 | pubmed:meshHeading | pubmed-meshheading:2884193-... | lld:pubmed |
| pubmed-article:2884193 | pubmed:meshHeading | pubmed-meshheading:2884193-... | lld:pubmed |
| pubmed-article:2884193 | pubmed:meshHeading | pubmed-meshheading:2884193-... | lld:pubmed |
| pubmed-article:2884193 | pubmed:meshHeading | pubmed-meshheading:2884193-... | lld:pubmed |
| pubmed-article:2884193 | pubmed:meshHeading | pubmed-meshheading:2884193-... | lld:pubmed |
| pubmed-article:2884193 | pubmed:meshHeading | pubmed-meshheading:2884193-... | lld:pubmed |
| pubmed-article:2884193 | pubmed:meshHeading | pubmed-meshheading:2884193-... | lld:pubmed |
| pubmed-article:2884193 | pubmed:meshHeading | pubmed-meshheading:2884193-... | lld:pubmed |
| pubmed-article:2884193 | pubmed:year | 1987 | lld:pubmed |
| pubmed-article:2884193 | pubmed:articleTitle | Changes in lymphocyte subsets after treatment with cyclophosphamide and during the development of contact sensitivity in the guinea pig. | lld:pubmed |
| pubmed-article:2884193 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2884193 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2884193 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2884193 | lld:pubmed |
