| pubmed-article:2872566 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2872566 | lifeskim:mentions | umls-concept:C0007765 | lld:lifeskim |
| pubmed-article:2872566 | lifeskim:mentions | umls-concept:C0596630 | lld:lifeskim |
| pubmed-article:2872566 | lifeskim:mentions | umls-concept:C0061465 | lld:lifeskim |
| pubmed-article:2872566 | pubmed:issue | 23 | lld:pubmed |
| pubmed-article:2872566 | pubmed:dateCreated | 1986-7-9 | lld:pubmed |
| pubmed-article:2872566 | pubmed:abstractText | Cultured cerebellar granule cells were found to exhibit calcium-dependent release of 3H-D-aspartate when stimulated with excitatory amino acids. L-glutamate and L-aspartate were found to be potent stimulators of 3H-D-aspartate release, D-aspartate was weaker and only minor effects were seen with D-glutamate, quisqualate, kainate, N-methyl-D-aspartate (NMDA) and L-alpha-aminoadipate (L-alpha AA). It was also found that only L-glutamate and L-aspartate showed high affinity for the 3H-L-glutamate binding sites on granule cell membranes. Stimulation by L-glutamate of 3H-D-aspartate release could be blocked by various excitatory amino acid antagonists. From the relative potencies of agonists and antagonists on D-aspartate release it is suggested that cerebellar granule cells express functionally active glutamate receptors with pharmacological characteristics different from all known excitatory amino acid receptors. | lld:pubmed |
| pubmed-article:2872566 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2872566 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2872566 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:2872566 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2872566 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2872566 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:2872566 | pubmed:issn | 0024-3205 | lld:pubmed |
| pubmed-article:2872566 | pubmed:author | pubmed-author:SchousboeAA | lld:pubmed |
| pubmed-article:2872566 | pubmed:author | pubmed-author:MeierEE | lld:pubmed |
| pubmed-article:2872566 | pubmed:author | pubmed-author:DrejerJJ | lld:pubmed |
| pubmed-article:2872566 | pubmed:author | pubmed-author:HonoréTT | lld:pubmed |
| pubmed-article:2872566 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2872566 | pubmed:day | 9 | lld:pubmed |
| pubmed-article:2872566 | pubmed:volume | 38 | lld:pubmed |
| pubmed-article:2872566 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2872566 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2872566 | pubmed:pagination | 2077-85 | lld:pubmed |
| pubmed-article:2872566 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:2872566 | pubmed:year | 1986 | lld:pubmed |
| pubmed-article:2872566 | pubmed:articleTitle | Pharmacologically distinct glutamate receptors on cerebellar granule cells. | lld:pubmed |
| pubmed-article:2872566 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2872566 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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