| pubmed-article:2851482 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2851482 | lifeskim:mentions | umls-concept:C0035143 | lld:lifeskim |
| pubmed-article:2851482 | lifeskim:mentions | umls-concept:C1412111 | lld:lifeskim |
| pubmed-article:2851482 | lifeskim:mentions | umls-concept:C1417038 | lld:lifeskim |
| pubmed-article:2851482 | lifeskim:mentions | umls-concept:C1979845 | lld:lifeskim |
| pubmed-article:2851482 | lifeskim:mentions | umls-concept:C1151970 | lld:lifeskim |
| pubmed-article:2851482 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:2851482 | pubmed:dateCreated | 1989-3-22 | lld:pubmed |
| pubmed-article:2851482 | pubmed:abstractText | The product of the MAT alpha 2 gene is a DNA-binding protein that acts as a repressor of two different sets of cell type-specific genes. In alpha cells, the alpha 2 protein represses the transcription of several a-specific genes. In a/alpha cells, the alpha 2 protein acts together with the product of the MATa1 gene, the a1 protein, to repress several genes used by haploids in the mating process. In addition to the mat alpha 2 mutations that result in defects in both types of regulation, other mat alpha 2 alleles have been described that result in defects in the repression of a-specific genes but that do not affect the ability of the alpha 2 and a1 proteins to interact to repress the haploid-specific genes. We report here the isolation of a new class of mat alpha 2 mutations that do not affect the ability of the alpha 2 protein to repress a-specific genes, but that interfere with the ability of the alpha 2 protein to interact with the a1 protein to repress the haploid-specific genes and establish the a/alpha cell type. These mutations may help determine the means by which the a1 protein interacts with alpha 2 to expand the set of genes under its control. | lld:pubmed |
| pubmed-article:2851482 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2851482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2851482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2851482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2851482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2851482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2851482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2851482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2851482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2851482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2851482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2851482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2851482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2851482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2851482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2851482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2851482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2851482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2851482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2851482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2851482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2851482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2851482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2851482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2851482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2851482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2851482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2851482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2851482 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2851482 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2851482 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2851482 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2851482 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2851482 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2851482 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2851482 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2851482 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:2851482 | pubmed:issn | 0016-6731 | lld:pubmed |
| pubmed-article:2851482 | pubmed:author | pubmed-author:ShaferBB | lld:pubmed |
| pubmed-article:2851482 | pubmed:author | pubmed-author:McGillCC | lld:pubmed |
| pubmed-article:2851482 | pubmed:author | pubmed-author:HicksJJ | lld:pubmed |
| pubmed-article:2851482 | pubmed:author | pubmed-author:StrathernJJ | lld:pubmed |
| pubmed-article:2851482 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2851482 | pubmed:volume | 120 | lld:pubmed |
| pubmed-article:2851482 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2851482 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2851482 | pubmed:pagination | 75-81 | lld:pubmed |
| pubmed-article:2851482 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:2851482 | pubmed:meshHeading | pubmed-meshheading:2851482-... | lld:pubmed |
| pubmed-article:2851482 | pubmed:meshHeading | pubmed-meshheading:2851482-... | lld:pubmed |
| pubmed-article:2851482 | pubmed:meshHeading | pubmed-meshheading:2851482-... | lld:pubmed |
| pubmed-article:2851482 | pubmed:meshHeading | pubmed-meshheading:2851482-... | lld:pubmed |
| pubmed-article:2851482 | pubmed:meshHeading | pubmed-meshheading:2851482-... | lld:pubmed |
| pubmed-article:2851482 | pubmed:meshHeading | pubmed-meshheading:2851482-... | lld:pubmed |
| pubmed-article:2851482 | pubmed:meshHeading | pubmed-meshheading:2851482-... | lld:pubmed |
| pubmed-article:2851482 | pubmed:meshHeading | pubmed-meshheading:2851482-... | lld:pubmed |
| pubmed-article:2851482 | pubmed:meshHeading | pubmed-meshheading:2851482-... | lld:pubmed |
| pubmed-article:2851482 | pubmed:meshHeading | pubmed-meshheading:2851482-... | lld:pubmed |
| pubmed-article:2851482 | pubmed:meshHeading | pubmed-meshheading:2851482-... | lld:pubmed |
| pubmed-article:2851482 | pubmed:meshHeading | pubmed-meshheading:2851482-... | lld:pubmed |
| pubmed-article:2851482 | pubmed:year | 1988 | lld:pubmed |
| pubmed-article:2851482 | pubmed:articleTitle | a/Alpha-specific repression by MAT alpha 2. | lld:pubmed |
| pubmed-article:2851482 | pubmed:affiliation | Laboratory of Eukaryotic Gene Expression, National Cancer Institute-Frederick Cancer Research Facility, Maryland 21701. | lld:pubmed |
| pubmed-article:2851482 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2851482 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2851482 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2851482 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2851482 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2851482 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2851482 | lld:pubmed |
