| pubmed-article:2846743 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2846743 | lifeskim:mentions | umls-concept:C0039194 | lld:lifeskim |
| pubmed-article:2846743 | lifeskim:mentions | umls-concept:C0034790 | lld:lifeskim |
| pubmed-article:2846743 | lifeskim:mentions | umls-concept:C0024518 | lld:lifeskim |
| pubmed-article:2846743 | lifeskim:mentions | umls-concept:C0108779 | lld:lifeskim |
| pubmed-article:2846743 | lifeskim:mentions | umls-concept:C1823153 | lld:lifeskim |
| pubmed-article:2846743 | lifeskim:mentions | umls-concept:C0678594 | lld:lifeskim |
| pubmed-article:2846743 | lifeskim:mentions | umls-concept:C0037791 | lld:lifeskim |
| pubmed-article:2846743 | lifeskim:mentions | umls-concept:C1705241 | lld:lifeskim |
| pubmed-article:2846743 | lifeskim:mentions | umls-concept:C0439097 | lld:lifeskim |
| pubmed-article:2846743 | lifeskim:mentions | umls-concept:C2349976 | lld:lifeskim |
| pubmed-article:2846743 | lifeskim:mentions | umls-concept:C1552644 | lld:lifeskim |
| pubmed-article:2846743 | lifeskim:mentions | umls-concept:C1547348 | lld:lifeskim |
| pubmed-article:2846743 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:2846743 | pubmed:dateCreated | 1988-12-20 | lld:pubmed |
| pubmed-article:2846743 | pubmed:abstractText | Analyses of TCR-bearing murine and human T cells have defined a unique subpopulation of T cells that express the TCR-gamma/delta proteins. The specificity of TCR-gamma/delta T cells and their role in the immune response have not yet been elucidated. Here we examine alloreactive TCR-gamma/delta T cell lines and clones that recognize MHC-encoded antigens. A BALB/c nu/nu (H-2d)-derived H-2k specific T cell line and derived clones were both cytolytic and released lymphokines after recognition of a non-classical H-2 antigen encoded in the TL region of the MHC. These cells expressed the V gamma 2/C gamma 1 protein in association with a TCR-delta gene product encoded by a Va gene segment rearranged to two D delta and one J delta variable elements. A second MHC-specific B10 nu/nu (H-2b) TCR-gamma/delta T cell line appeared to recognize a classical H-2D-encoded MHC molecule and expressed a distinct V gamma/C gamma 4-encoded protein. These data suggest that many TCR-gamma/delta-expressing T cells may recognize MHC-linked antigens encoded within distinct subregions of the MHC. The role of MHC-specific TCR-gamma/delta cells in immune responses and their immunological significance are discussed. | lld:pubmed |
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| pubmed-article:2846743 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2846743 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2846743 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:2846743 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2846743 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2846743 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:2846743 | pubmed:issn | 0022-1007 | lld:pubmed |
| pubmed-article:2846743 | pubmed:author | pubmed-author:BluestoneJ... | lld:pubmed |
| pubmed-article:2846743 | pubmed:author | pubmed-author:CronR QRQ | lld:pubmed |
| pubmed-article:2846743 | pubmed:author | pubmed-author:MatisL ALA | lld:pubmed |
| pubmed-article:2846743 | pubmed:author | pubmed-author:HouldenB ABA | lld:pubmed |
| pubmed-article:2846743 | pubmed:author | pubmed-author:CottermanMM | lld:pubmed |
| pubmed-article:2846743 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2846743 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:2846743 | pubmed:volume | 168 | lld:pubmed |
| pubmed-article:2846743 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2846743 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2846743 | pubmed:pagination | 1899-916 | lld:pubmed |
| pubmed-article:2846743 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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