| pubmed-article:2844604 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2844604 | lifeskim:mentions | umls-concept:C0006675 | lld:lifeskim |
| pubmed-article:2844604 | lifeskim:mentions | umls-concept:C0005821 | lld:lifeskim |
| pubmed-article:2844604 | lifeskim:mentions | umls-concept:C0023823 | lld:lifeskim |
| pubmed-article:2844604 | lifeskim:mentions | umls-concept:C0178719 | lld:lifeskim |
| pubmed-article:2844604 | lifeskim:mentions | umls-concept:C0442805 | lld:lifeskim |
| pubmed-article:2844604 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:2844604 | pubmed:dateCreated | 1988-11-14 | lld:pubmed |
| pubmed-article:2844604 | pubmed:abstractText | Low-density lipoproteins activate isolated human platelets. The mechanism of this activation is unknown, but may involve increased phosphoinositide turnover. We have examined the effect of low-density lipoproteins on intracellular calcium concentrations in platelets loaded with the photoprotein aequorin. The lipoproteins induced concentration-dependent increases in intracellular calcium, associated with shape change and aggregation. These responses could be partially inhibited by the removal of extracellular calcium and by pre-incubation with acetylsalicylic acid. They were also antagonised by agents which increase cellular concentrations of cyclic adenosine and guanosine monophosphates. It is not clear whether the platelet-lipoprotein interaction involves a 'classical' lipoprotein receptor. | lld:pubmed |
| pubmed-article:2844604 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2844604 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2844604 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2844604 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2844604 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2844604 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2844604 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2844604 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2844604 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2844604 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2844604 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2844604 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2844604 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2844604 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2844604 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2844604 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:2844604 | pubmed:issn | 0014-5793 | lld:pubmed |
| pubmed-article:2844604 | pubmed:author | pubmed-author:BruckdorferK... | lld:pubmed |
| pubmed-article:2844604 | pubmed:author | pubmed-author:SeverP SPS | lld:pubmed |
| pubmed-article:2844604 | pubmed:author | pubmed-author:SchachterMM | lld:pubmed |
| pubmed-article:2844604 | pubmed:author | pubmed-author:DunnR CRC | lld:pubmed |
| pubmed-article:2844604 | pubmed:author | pubmed-author:FeherM DMD | lld:pubmed |
| pubmed-article:2844604 | pubmed:author | pubmed-author:TranterP RPR | lld:pubmed |
| pubmed-article:2844604 | pubmed:author | pubmed-author:MilesC MCM | lld:pubmed |
| pubmed-article:2844604 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2844604 | pubmed:day | 10 | lld:pubmed |
| pubmed-article:2844604 | pubmed:volume | 238 | lld:pubmed |
| pubmed-article:2844604 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2844604 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2844604 | pubmed:pagination | 357-60 | lld:pubmed |
| pubmed-article:2844604 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:2844604 | pubmed:meshHeading | pubmed-meshheading:2844604-... | lld:pubmed |
| pubmed-article:2844604 | pubmed:meshHeading | pubmed-meshheading:2844604-... | lld:pubmed |
| pubmed-article:2844604 | pubmed:meshHeading | pubmed-meshheading:2844604-... | lld:pubmed |
| pubmed-article:2844604 | pubmed:meshHeading | pubmed-meshheading:2844604-... | lld:pubmed |
| pubmed-article:2844604 | pubmed:meshHeading | pubmed-meshheading:2844604-... | lld:pubmed |
| pubmed-article:2844604 | pubmed:meshHeading | pubmed-meshheading:2844604-... | lld:pubmed |
| pubmed-article:2844604 | pubmed:meshHeading | pubmed-meshheading:2844604-... | lld:pubmed |
| pubmed-article:2844604 | pubmed:meshHeading | pubmed-meshheading:2844604-... | lld:pubmed |
| pubmed-article:2844604 | pubmed:meshHeading | pubmed-meshheading:2844604-... | lld:pubmed |
| pubmed-article:2844604 | pubmed:meshHeading | pubmed-meshheading:2844604-... | lld:pubmed |
| pubmed-article:2844604 | pubmed:meshHeading | pubmed-meshheading:2844604-... | lld:pubmed |
| pubmed-article:2844604 | pubmed:meshHeading | pubmed-meshheading:2844604-... | lld:pubmed |
| pubmed-article:2844604 | pubmed:meshHeading | pubmed-meshheading:2844604-... | lld:pubmed |
| pubmed-article:2844604 | pubmed:year | 1988 | lld:pubmed |
| pubmed-article:2844604 | pubmed:articleTitle | Low-density lipoproteins increase intracellular calcium in aequorin-loaded platelets. | lld:pubmed |
| pubmed-article:2844604 | pubmed:affiliation | Department of Biochemistry, Royal Free Hospital School of Medicine, London, England. | lld:pubmed |
| pubmed-article:2844604 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2844604 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2844604 | lld:pubmed |
