Consequences of molecular recognition in the S1-S2 intersubsite region of papain for catalytic-site chemistry. Change in pH-dependence characteristics and generation of an inverse solvent kinetic isotope effect by introduction of a P1-P2 amide bond into a two-protonic-state reactivity probe.

Source:http://linkedlifedata.com/resource/pubmed/id/2839145

Biochem. J. 1988 Mar 15 250 3 761-72

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2839145