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pubmed-article:2838824pubmed:abstractTextA protected 2-aminopurine nucleoside suitable for incorporation into oligodeoxynucleotides using phosphite triester chemical synthesis procedures has been prepared via oxidation of a purine hydrazino derivative with silver (I) oxide. Five oligodeoxynucleotides containing Eco RI and Bam HI recognition sites have been prepared such that, in the double stranded form, the 2-aminopurine base has either a complementary thymine or cytosine nucleobase. The helix character and thermodynamic parameters for helix formation have been examined.lld:pubmed
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pubmed-article:2838824pubmed:articleTitleA new approach to the synthesis of a protected 2-aminopurine derivative and its incorporation into oligodeoxynucleotides containing the Eco RI and Bam HI recognition sites.lld:pubmed
pubmed-article:2838824pubmed:affiliationDepartment of Chemistry, Boston College, Chestnut Hill, MA 02167.lld:pubmed
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