| pubmed-article:2820228 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2820228 | lifeskim:mentions | umls-concept:C0032961 | lld:lifeskim |
| pubmed-article:2820228 | lifeskim:mentions | umls-concept:C0377511 | lld:lifeskim |
| pubmed-article:2820228 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:2820228 | pubmed:dateCreated | 1987-10-22 | lld:pubmed |
| pubmed-article:2820228 | pubmed:abstractText | Our aims were to determine the potential usefulness of digoxin-like immunoreactive substances in the prediction of preeclampsia, to study the relationship between fetal production of these substances and maternal serum levels, and to evaluate the association between digoxin-like immunoreactive substances and plasma volume findings in preeclamptic pregnancies. Serum digoxin-like immunoreactive substance concentrations were measured in normotensive and preeclamptic pregnant women and in umbilical artery and vein blood samples. None of the patients in the first trimester (n = 53) and 11% of those in the second (n = 56) had detectable levels of this substance. However, 91% of the patients in the third trimester (n = 161) had positive results. The concentrations of digoxin-like immunoreactive substances in the preeclamptic group (n = 78) were significantly (p less than 0.005) lower than those of third-trimester (n = 83) normotensive patients (0.22 +/- 0.12 versus 0.32 +/- 0.15 ng/ml). However, there were no significant differences between the two groups regarding digoxin-like immunoreactive substance concentrations when matched for gestational age (41 patients in each group). Digoxin-like immunoreactive substance concentrations in umbilical vessels were significantly higher (p less than 0.001) than the corresponding maternal levels. Umbilical vessel digoxin-like immunoreactive substance levels demonstrated good correlation with fetal gestational age and birth weight in both normotensive and preeclamptic pregnancies. On the other hand, there was a poor (r = 0.02; p = 0.91) correlation between plasma volume findings and digoxin-like immunoreactive substance concentration. We conclude that the digoxin-like immunoreactive substance level may be of very little value in the prediction of preeclampsia. The presence of digoxin-like immunoreactive substance at greater concentrations in the umbilical cord blood samples suggests the possibility of the fetus as the source of this substance. Digoxin-like immunoreactive substances may not play a major role in plasma volume expansion during pregnancy. | lld:pubmed |
| pubmed-article:2820228 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2820228 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2820228 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:2820228 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2820228 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2820228 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2820228 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2820228 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2820228 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2820228 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2820228 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:2820228 | pubmed:issn | 0002-9378 | lld:pubmed |
| pubmed-article:2820228 | pubmed:author | pubmed-author:SibaiB MBM | lld:pubmed |
| pubmed-article:2820228 | pubmed:author | pubmed-author:PhelpsS JSJ | lld:pubmed |
| pubmed-article:2820228 | pubmed:author | pubmed-author:CochranE BEB | lld:pubmed |
| pubmed-article:2820228 | pubmed:author | pubmed-author:GonzálezA RAR | lld:pubmed |
| pubmed-article:2820228 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2820228 | pubmed:volume | 157 | lld:pubmed |
| pubmed-article:2820228 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2820228 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2820228 | pubmed:pagination | 660-4 | lld:pubmed |
| pubmed-article:2820228 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
| pubmed-article:2820228 | pubmed:meshHeading | pubmed-meshheading:2820228-... | lld:pubmed |
| pubmed-article:2820228 | pubmed:meshHeading | pubmed-meshheading:2820228-... | lld:pubmed |
| pubmed-article:2820228 | pubmed:meshHeading | pubmed-meshheading:2820228-... | lld:pubmed |
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| pubmed-article:2820228 | pubmed:meshHeading | pubmed-meshheading:2820228-... | lld:pubmed |
| pubmed-article:2820228 | pubmed:meshHeading | pubmed-meshheading:2820228-... | lld:pubmed |
| pubmed-article:2820228 | pubmed:meshHeading | pubmed-meshheading:2820228-... | lld:pubmed |
| pubmed-article:2820228 | pubmed:meshHeading | pubmed-meshheading:2820228-... | lld:pubmed |
| pubmed-article:2820228 | pubmed:meshHeading | pubmed-meshheading:2820228-... | lld:pubmed |
| pubmed-article:2820228 | pubmed:meshHeading | pubmed-meshheading:2820228-... | lld:pubmed |
| pubmed-article:2820228 | pubmed:meshHeading | pubmed-meshheading:2820228-... | lld:pubmed |
| pubmed-article:2820228 | pubmed:year | 1987 | lld:pubmed |
| pubmed-article:2820228 | pubmed:articleTitle | Digoxin-like immunoreactive substance in pregnancy. | lld:pubmed |
| pubmed-article:2820228 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2820228 | lld:pubmed |
