| pubmed-article:2809914 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2809914 | lifeskim:mentions | umls-concept:C0021288 | lld:lifeskim |
| pubmed-article:2809914 | lifeskim:mentions | umls-concept:C0032105 | lld:lifeskim |
| pubmed-article:2809914 | lifeskim:mentions | umls-concept:C0023820 | lld:lifeskim |
| pubmed-article:2809914 | lifeskim:mentions | umls-concept:C0086045 | lld:lifeskim |
| pubmed-article:2809914 | lifeskim:mentions | umls-concept:C0023779 | lld:lifeskim |
| pubmed-article:2809914 | lifeskim:mentions | umls-concept:C0030547 | lld:lifeskim |
| pubmed-article:2809914 | lifeskim:mentions | umls-concept:C1442162 | lld:lifeskim |
| pubmed-article:2809914 | lifeskim:mentions | umls-concept:C0014020 | lld:lifeskim |
| pubmed-article:2809914 | lifeskim:mentions | umls-concept:C0439165 | lld:lifeskim |
| pubmed-article:2809914 | lifeskim:mentions | umls-concept:C1550718 | lld:lifeskim |
| pubmed-article:2809914 | pubmed:issue | 5 Pt 1 | lld:pubmed |
| pubmed-article:2809914 | pubmed:dateCreated | 1989-12-5 | lld:pubmed |
| pubmed-article:2809914 | pubmed:abstractText | Because 10% and 20% intravenously administered lipid emulsions (intralipid preparations) differ in their phospholipid/triglyceride ratio (0.12 and 0.06, respectively), 28 low birth weight infants requiring parenteral nutrition for at least 1 week were selected at random to receive either emulsion to determine the effects on plasma lipids and lipoproteins. Triglyceride intake was progressively increased to reach 2 gm/kg per day between days 4 and 7. During that period, all plasma lipids in samples taken 6 hours after infusion were higher in the 10% intralipid group. In comparison with day 0 values, triglyceride concentrations decreased (63 +/- 7 to 45 +/- 4 mg/dl; p less than 0.05) in the 20% group. Cholesterol levels increased in both groups, but the rise was more than twofold higher in the 10% group. Phospholipid increase was approximately 25% in the 20% group but more than 125% in patients receiving the 10% emulsion (p less than 0.005). The changes in plasma cholesterol and phospholipid levels were almost entirely in low-density lipoproteins. After 7 days, eight infants from each group were given the alternate emulsion, which resulted in a reversal of lipid patterns in each patient. We conclude that the higher phospholipid intake in 10% than in 20% intralipid is associated with higher plasma triglyceride concentrations and leads to accumulation of cholesterol and phospholipids in low-density lipoproteins. Emulsions with lower phospholipid content may be preferable for low birth weight infants and perhaps other patient populations with impaired removal of parenteral fat emulsions. | lld:pubmed |
| pubmed-article:2809914 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2809914 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2809914 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2809914 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2809914 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:2809914 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2809914 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:2809914 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2809914 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2809914 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2809914 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2809914 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2809914 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:2809914 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2809914 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2809914 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:2809914 | pubmed:issn | 0022-3476 | lld:pubmed |
| pubmed-article:2809914 | pubmed:author | pubmed-author:CoussaertEE | lld:pubmed |
| pubmed-article:2809914 | pubmed:author | pubmed-author:CarpentierY... | lld:pubmed |
| pubmed-article:2809914 | pubmed:author | pubmed-author:DeckelbaumR... | lld:pubmed |
| pubmed-article:2809914 | pubmed:author | pubmed-author:HaumontDD | lld:pubmed |
| pubmed-article:2809914 | pubmed:author | pubmed-author:RichelleMM | lld:pubmed |
| pubmed-article:2809914 | pubmed:author | pubmed-author:BihainB EBE | lld:pubmed |
| pubmed-article:2809914 | pubmed:author | pubmed-author:DahlanWW | lld:pubmed |
| pubmed-article:2809914 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2809914 | pubmed:volume | 115 | lld:pubmed |
| pubmed-article:2809914 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2809914 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2809914 | pubmed:pagination | 787-93 | lld:pubmed |
| pubmed-article:2809914 | pubmed:dateRevised | 2010-11-18 | lld:pubmed |
| pubmed-article:2809914 | pubmed:meshHeading | pubmed-meshheading:2809914-... | lld:pubmed |
| pubmed-article:2809914 | pubmed:meshHeading | pubmed-meshheading:2809914-... | lld:pubmed |
| pubmed-article:2809914 | pubmed:meshHeading | pubmed-meshheading:2809914-... | lld:pubmed |
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| pubmed-article:2809914 | pubmed:meshHeading | pubmed-meshheading:2809914-... | lld:pubmed |
| pubmed-article:2809914 | pubmed:meshHeading | pubmed-meshheading:2809914-... | lld:pubmed |
| pubmed-article:2809914 | pubmed:year | 1989 | lld:pubmed |
| pubmed-article:2809914 | pubmed:articleTitle | Plasma lipid and plasma lipoprotein concentrations in low birth weight infants given parenteral nutrition with twenty or ten percent lipid emulsion. | lld:pubmed |
| pubmed-article:2809914 | pubmed:affiliation | Neonatal Unit, Saint-Pierre Hospital, Vrije Universiteit, Brussels, Belgium. | lld:pubmed |
| pubmed-article:2809914 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2809914 | pubmed:publicationType | Clinical Trial | lld:pubmed |
| pubmed-article:2809914 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:2809914 | pubmed:publicationType | Randomized Controlled Trial | lld:pubmed |
| pubmed-article:2809914 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2809914 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2809914 | lld:pubmed |
