| pubmed-article:2784398 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2784398 | lifeskim:mentions | umls-concept:C0035820 | lld:lifeskim |
| pubmed-article:2784398 | lifeskim:mentions | umls-concept:C0001554 | lld:lifeskim |
| pubmed-article:2784398 | lifeskim:mentions | umls-concept:C0920317 | lld:lifeskim |
| pubmed-article:2784398 | lifeskim:mentions | umls-concept:C0019080 | lld:lifeskim |
| pubmed-article:2784398 | lifeskim:mentions | umls-concept:C0014245 | lld:lifeskim |
| pubmed-article:2784398 | lifeskim:mentions | umls-concept:C0036435 | lld:lifeskim |
| pubmed-article:2784398 | lifeskim:mentions | umls-concept:C1273870 | lld:lifeskim |
| pubmed-article:2784398 | lifeskim:mentions | umls-concept:C0443252 | lld:lifeskim |
| pubmed-article:2784398 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:2784398 | pubmed:dateCreated | 1989-4-27 | lld:pubmed |
| pubmed-article:2784398 | pubmed:abstractText | Seven randomized clinical trials evaluating the effect of repeated endoscopic variceal sclerotherapy on the long-term survival of patients with variceal hemorrhage have been published in the English-language literature. In four trials, the sclerotherapy-treated patients showed an improved long-term survival (follow-up periods longer than a year) when compared with patients in the medical regimen group, whereas in the other three trials, the long-term survival did not differ between the compared groups. Sample sizes in these "negative" trials were too small to detect a true moderate effect for serial sclerotherapy. To resolve this controversy, we combined the findings from all trials using a meta-analysis and determined the overall effect of repeated endoscopic variceal sclerotherapy on the survival of patients who had previously bled from esophageal varices. An overall risk difference of -0.15 (95% confidence limits, -0.21 to -0.08; p less than 0.0005) was estimated, indicating that sclerotherapy reduced the number of deaths by 25%. The estimated overall risk difference remained negative even when all patients in the sclerotherapy group with an unknown survival status were pessimistically considered dead at the end of the follow-up period. The results of this quantitative synthesis suggest that patients with bleeding esophageal varices benefit from the inclusion of repeated sclerotherapy in their long-term management regimen. | lld:pubmed |
| pubmed-article:2784398 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2784398 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2784398 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:2784398 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2784398 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2784398 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:2784398 | pubmed:issn | 0016-5085 | lld:pubmed |
| pubmed-article:2784398 | pubmed:author | pubmed-author:VilleneuveJ... | lld:pubmed |
| pubmed-article:2784398 | pubmed:author | pubmed-author:Infante-Rivar... | lld:pubmed |
| pubmed-article:2784398 | pubmed:author | pubmed-author:EsnaolaSS | lld:pubmed |
| pubmed-article:2784398 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2784398 | pubmed:volume | 96 | lld:pubmed |
| pubmed-article:2784398 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2784398 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2784398 | pubmed:pagination | 1087-92 | lld:pubmed |
| pubmed-article:2784398 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
| pubmed-article:2784398 | pubmed:meshHeading | pubmed-meshheading:2784398-... | lld:pubmed |
| pubmed-article:2784398 | pubmed:meshHeading | pubmed-meshheading:2784398-... | lld:pubmed |
| pubmed-article:2784398 | pubmed:meshHeading | pubmed-meshheading:2784398-... | lld:pubmed |
| pubmed-article:2784398 | pubmed:meshHeading | pubmed-meshheading:2784398-... | lld:pubmed |
| pubmed-article:2784398 | pubmed:meshHeading | pubmed-meshheading:2784398-... | lld:pubmed |
| pubmed-article:2784398 | pubmed:meshHeading | pubmed-meshheading:2784398-... | lld:pubmed |
| pubmed-article:2784398 | pubmed:meshHeading | pubmed-meshheading:2784398-... | lld:pubmed |
| pubmed-article:2784398 | pubmed:meshHeading | pubmed-meshheading:2784398-... | lld:pubmed |
| pubmed-article:2784398 | pubmed:year | 1989 | lld:pubmed |
| pubmed-article:2784398 | pubmed:articleTitle | Role of endoscopic variceal sclerotherapy in the long-term management of variceal bleeding: a meta-analysis. | lld:pubmed |
| pubmed-article:2784398 | pubmed:affiliation | School of Occupational Health, McGill University, Montreal, Canada. | lld:pubmed |
| pubmed-article:2784398 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2784398 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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