pubmed-article:2719664 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:2719664 | lifeskim:mentions | umls-concept:C0598154 | lld:lifeskim |
pubmed-article:2719664 | lifeskim:mentions | umls-concept:C0286104 | lld:lifeskim |
pubmed-article:2719664 | pubmed:issue | 2 | lld:pubmed |
pubmed-article:2719664 | pubmed:dateCreated | 1989-6-20 | lld:pubmed |
pubmed-article:2719664 | pubmed:abstractText | The metabolism of 14C- and 36Cl-labelled 1,6-dichloro-1,6-dideoxyfructose (DCF) was studied in the isolated perfused rat liver system. Dechlorination of DCF occurred in the liver and erythrocytes and was GSH-dependent. The GSH conjugate formed was identified by 13C and 1H n.m.r. as the 6-chlorofructos-1-yl-SG conjugate. It is proposed that the GS- anion attacks the low steady-state concentration of the reactive keto form of DCF and that the conjugate formed cyclizes to the dominant beta-anomer. 6-Chlorofructos-1-yl-SG conjugate of hepatic origin is excreted into bile, whereas that produced in erythrocytes does not enter the liver. | lld:pubmed |
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pubmed-article:2719664 | pubmed:language | eng | lld:pubmed |
pubmed-article:2719664 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2719664 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:2719664 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2719664 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2719664 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2719664 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:2719664 | pubmed:month | Apr | lld:pubmed |
pubmed-article:2719664 | pubmed:issn | 0264-6021 | lld:pubmed |
pubmed-article:2719664 | pubmed:author | pubmed-author:SandersJ KJK | lld:pubmed |
pubmed-article:2719664 | pubmed:author | pubmed-author:DanielJ WJW | lld:pubmed |
pubmed-article:2719664 | pubmed:author | pubmed-author:CrawfordAA | lld:pubmed |
pubmed-article:2719664 | pubmed:author | pubmed-author:CurtisC GCG | lld:pubmed |
pubmed-article:2719664 | pubmed:author | pubmed-author:PowellG MGM | lld:pubmed |
pubmed-article:2719664 | pubmed:author | pubmed-author:SnodinD JDJ | lld:pubmed |
pubmed-article:2719664 | pubmed:author | pubmed-author:HughesH MHM | lld:pubmed |
pubmed-article:2719664 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:2719664 | pubmed:day | 15 | lld:pubmed |
pubmed-article:2719664 | pubmed:volume | 259 | lld:pubmed |
pubmed-article:2719664 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:2719664 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:2719664 | pubmed:pagination | 537-43 | lld:pubmed |
pubmed-article:2719664 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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pubmed-article:2719664 | pubmed:year | 1989 | lld:pubmed |
pubmed-article:2719664 | pubmed:articleTitle | Glutathione-dependent dechlorination of 1,6-dichloro-1,6-dideoxyfructose. | lld:pubmed |
pubmed-article:2719664 | pubmed:affiliation | Department of Biochemistry, University of Wales College of Cardiff, U.K. | lld:pubmed |
pubmed-article:2719664 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:2719664 | pubmed:publicationType | In Vitro | lld:pubmed |
pubmed-article:2719664 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |