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pubmed-article:2714635pubmed:abstractTextThe role of recBC functions has been tested for three types of chromosomal recombination events: (1) recombination between direct repeats to generate a deletion, (2) recombination between a small circular fragment and the chromosome, and (3) recombination between inversely oriented repeats to form an inversion. Deletion formation by recombination between direct repeats, which does not require a fully reciprocal exchange, is independent of recBC function. Circle integration and inversion formation are both stimulated by the recBC function; these events require full reciprocality. The results suggest that half-reciprocal exchanges can occur without recBC, but recBC functions greatly stimulate completion of a fully reciprocal exchange. We propose that chromosomal recombination is a two-step process, and recBC functions are primarily required for the second step.lld:pubmed
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pubmed-article:2714635pubmed:articleTitleRole of recBC function in formation of chromosomal rearrangements: a two-step model for recombination.lld:pubmed
pubmed-article:2714635pubmed:affiliationDepartment of Biology, University of Utah, Salt Lake City 84112.lld:pubmed
pubmed-article:2714635pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:2714635pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
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