Linked Life Data

2708182

Source:http://linkedlifedata.com/resource/pubmed/id/2708182

Statements in which the resource exists.
SubjectPredicateObjectContext
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pubmed-article:2708182pubmed:abstractTextA study on the biochemical and ultrastructural effects of isatin on Echinococcus multilocularis metacestodes in Meriones unguiculatus is reported. In the metacestode, after an 18 day treatment period, the alkaline phosphatase and lactate dehydrogenase activities decreased and the acid phosphatase activity increased. Glucose and glycogen stores declined significantly. Examinations of the ultrastructure revealed an increase of lysosomes and phagocytic reactions. The protoscolesces were damaged and an abnormal striated process appeared. The tegumental cytoplasmic syncytium remained unaltered. These observations suggest that isatin derivatives may have a role in the chemotherapy of infections caused by Echinococcus spp.lld:pubmed
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pubmed-article:2708182pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:2708182pubmed:articleTitleEchinococcus multilocularis metacestodes: biochemical and ultrastructural investigations on the effect of isatin (2-3 indoline dione) in vivo.lld:pubmed
pubmed-article:2708182pubmed:affiliationLaboratoire de Parasitologie et de Chimie Thérapeutique-U.C.B., Lyon.lld:pubmed
pubmed-article:2708182pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:2708182pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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