| pubmed-article:2669746 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2669746 | lifeskim:mentions | umls-concept:C0206131 | lld:lifeskim |
| pubmed-article:2669746 | lifeskim:mentions | umls-concept:C0016030 | lld:lifeskim |
| pubmed-article:2669746 | lifeskim:mentions | umls-concept:C0007589 | lld:lifeskim |
| pubmed-article:2669746 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:2669746 | lifeskim:mentions | umls-concept:C1511938 | lld:lifeskim |
| pubmed-article:2669746 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:2669746 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:2669746 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:2669746 | pubmed:dateCreated | 1989-9-21 | lld:pubmed |
| pubmed-article:2669746 | pubmed:abstractText | The objective of this study was to examine the expression of the c-raf-1 and A-rat-1 protooncogenes during differentiation of 3T3-L1 preadipocytes into adipocytes. At confluence, prior to initiation of differentiation c-raf and A-raf steady state mRNA levels were low. Expression of c-raf and A-raf began to increase 72 hours following initiation of differentiation by treatment with differentiation medium, reaching a maximum increase of 3 to 6-fold and 3 to 4-fold respectively by 190 hours. The increase of c-raf and A-raf steady state message levels occurred concomitant with the onset of differentiation as indicated by increased levels of glycerol-3-phosphate dehydrogenase mRNA. These changes were compared with those for several other protooncogene mRNAs including c-myc, c-fos, H-ras and histone H3. These results are the first to show increase expression of the raf protooncogenes during terminal differentiation rather than in association with proliferation. | lld:pubmed |
| pubmed-article:2669746 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2669746 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2669746 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2669746 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2669746 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2669746 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2669746 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2669746 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2669746 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2669746 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2669746 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2669746 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2669746 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2669746 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2669746 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:2669746 | pubmed:issn | 0006-291X | lld:pubmed |
| pubmed-article:2669746 | pubmed:author | pubmed-author:GouldG WGW | lld:pubmed |
| pubmed-article:2669746 | pubmed:author | pubmed-author:YagerJ DJD | lld:pubmed |
| pubmed-article:2669746 | pubmed:author | pubmed-author:ZmuidzinasAA | lld:pubmed |
| pubmed-article:2669746 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2669746 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:2669746 | pubmed:volume | 162 | lld:pubmed |
| pubmed-article:2669746 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2669746 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2669746 | pubmed:pagination | 1180-7 | lld:pubmed |
| pubmed-article:2669746 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
| pubmed-article:2669746 | pubmed:meshHeading | pubmed-meshheading:2669746-... | lld:pubmed |
| pubmed-article:2669746 | pubmed:meshHeading | pubmed-meshheading:2669746-... | lld:pubmed |
| pubmed-article:2669746 | pubmed:meshHeading | pubmed-meshheading:2669746-... | lld:pubmed |
| pubmed-article:2669746 | pubmed:meshHeading | pubmed-meshheading:2669746-... | lld:pubmed |
| pubmed-article:2669746 | pubmed:meshHeading | pubmed-meshheading:2669746-... | lld:pubmed |
| pubmed-article:2669746 | pubmed:meshHeading | pubmed-meshheading:2669746-... | lld:pubmed |
| pubmed-article:2669746 | pubmed:meshHeading | pubmed-meshheading:2669746-... | lld:pubmed |
| pubmed-article:2669746 | pubmed:meshHeading | pubmed-meshheading:2669746-... | lld:pubmed |
| pubmed-article:2669746 | pubmed:meshHeading | pubmed-meshheading:2669746-... | lld:pubmed |
| pubmed-article:2669746 | pubmed:meshHeading | pubmed-meshheading:2669746-... | lld:pubmed |
| pubmed-article:2669746 | pubmed:meshHeading | pubmed-meshheading:2669746-... | lld:pubmed |
| pubmed-article:2669746 | pubmed:meshHeading | pubmed-meshheading:2669746-... | lld:pubmed |
| pubmed-article:2669746 | pubmed:meshHeading | pubmed-meshheading:2669746-... | lld:pubmed |
| pubmed-article:2669746 | pubmed:year | 1989 | lld:pubmed |
| pubmed-article:2669746 | pubmed:articleTitle | Expression of c-raf-1 and A-raf-1 during differentiation of 3T3-L1 preadipocyte fibroblasts into adipocytes. | lld:pubmed |
| pubmed-article:2669746 | pubmed:affiliation | Department of Biochemistry, Dartmouth Medical School Hanover, NH 03756. | lld:pubmed |
| pubmed-article:2669746 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2669746 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:2669746 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2669746 | lld:pubmed |
