| pubmed-article:2655719 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2655719 | lifeskim:mentions | umls-concept:C0029921 | lld:lifeskim |
| pubmed-article:2655719 | lifeskim:mentions | umls-concept:C0013227 | lld:lifeskim |
| pubmed-article:2655719 | lifeskim:mentions | umls-concept:C0344315 | lld:lifeskim |
| pubmed-article:2655719 | lifeskim:mentions | umls-concept:C1704632 | lld:lifeskim |
| pubmed-article:2655719 | lifeskim:mentions | umls-concept:C0871261 | lld:lifeskim |
| pubmed-article:2655719 | lifeskim:mentions | umls-concept:C2911692 | lld:lifeskim |
| pubmed-article:2655719 | lifeskim:mentions | umls-concept:C1706817 | lld:lifeskim |
| pubmed-article:2655719 | lifeskim:mentions | umls-concept:C0392756 | lld:lifeskim |
| pubmed-article:2655719 | lifeskim:mentions | umls-concept:C0681842 | lld:lifeskim |
| pubmed-article:2655719 | lifeskim:mentions | umls-concept:C0599265 | lld:lifeskim |
| pubmed-article:2655719 | lifeskim:mentions | umls-concept:C0560134 | lld:lifeskim |
| pubmed-article:2655719 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:2655719 | pubmed:dateCreated | 1989-7-6 | lld:pubmed |
| pubmed-article:2655719 | pubmed:abstractText | Forty-two outpatients with major depressive disorder entered a double-blind, randomized trial of either desipramine or amitriptyline for a minimum of 6 weeks. Pretreatment polysomnographic and clinical measures were used to predict response. Response was defined as a 17-item Hamilton Rating Scale for Depression score less than or equal to 9 at the end of treatment. There was a 61.1% response rate for patients treated with amitriptyline and a 66.7% response rate for patients treated with desipramine. Reduced REM latency (2-night mean less than or equal to 65.0 min) predicted a positive response to these tricyclic antidepressants. REM latency did not differentiate between desipramine or amitriptyline responders. More patients with reduced REM latency (80%) responded to treatment compared with patients with nonreduced REM latency (50%). The 80% response rate in reduced REM latency depressed patients confirms our previous findings in a mixed inpatient and outpatient sample. Contrary to our hypothesis, in this sample, endogenous depression was not associated with a good response to tricyclic medication. | lld:pubmed |
| pubmed-article:2655719 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2655719 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2655719 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2655719 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2655719 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2655719 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2655719 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2655719 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2655719 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2655719 | pubmed:month | May | lld:pubmed |
| pubmed-article:2655719 | pubmed:issn | 0006-3223 | lld:pubmed |
| pubmed-article:2655719 | pubmed:author | pubmed-author:OrsulakP JPJ | lld:pubmed |
| pubmed-article:2655719 | pubmed:author | pubmed-author:RushA JAJ | lld:pubmed |
| pubmed-article:2655719 | pubmed:author | pubmed-author:RoffwargH PHP | lld:pubmed |
| pubmed-article:2655719 | pubmed:author | pubmed-author:Weissenburger... | lld:pubmed |
| pubmed-article:2655719 | pubmed:author | pubmed-author:GilesD EDE | lld:pubmed |
| pubmed-article:2655719 | pubmed:author | pubmed-author:JarrettR BRB | lld:pubmed |
| pubmed-article:2655719 | pubmed:author | pubmed-author:Feldman-Koffl... | lld:pubmed |
| pubmed-article:2655719 | pubmed:author | pubmed-author:DebusJ RJR | lld:pubmed |
| pubmed-article:2655719 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2655719 | pubmed:volume | 26 | lld:pubmed |
| pubmed-article:2655719 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2655719 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2655719 | pubmed:pagination | 61-72 | lld:pubmed |
| pubmed-article:2655719 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
| pubmed-article:2655719 | pubmed:meshHeading | pubmed-meshheading:2655719-... | lld:pubmed |
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| pubmed-article:2655719 | pubmed:meshHeading | pubmed-meshheading:2655719-... | lld:pubmed |
| pubmed-article:2655719 | pubmed:meshHeading | pubmed-meshheading:2655719-... | lld:pubmed |
| pubmed-article:2655719 | pubmed:meshHeading | pubmed-meshheading:2655719-... | lld:pubmed |
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| pubmed-article:2655719 | pubmed:meshHeading | pubmed-meshheading:2655719-... | lld:pubmed |
| pubmed-article:2655719 | pubmed:meshHeading | pubmed-meshheading:2655719-... | lld:pubmed |
| pubmed-article:2655719 | pubmed:meshHeading | pubmed-meshheading:2655719-... | lld:pubmed |
| pubmed-article:2655719 | pubmed:meshHeading | pubmed-meshheading:2655719-... | lld:pubmed |
| pubmed-article:2655719 | pubmed:meshHeading | pubmed-meshheading:2655719-... | lld:pubmed |
| pubmed-article:2655719 | pubmed:meshHeading | pubmed-meshheading:2655719-... | lld:pubmed |
| pubmed-article:2655719 | pubmed:meshHeading | pubmed-meshheading:2655719-... | lld:pubmed |
| pubmed-article:2655719 | pubmed:year | 1989 | lld:pubmed |
| pubmed-article:2655719 | pubmed:articleTitle | Reduced REM latency predicts response to tricyclic medication in depressed outpatients. | lld:pubmed |
| pubmed-article:2655719 | pubmed:affiliation | Mental Health Clinical Research Center, University of Texas Southwestern Medical Center at Dallas 75235. | lld:pubmed |
| pubmed-article:2655719 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2655719 | pubmed:publicationType | Clinical Trial | lld:pubmed |
| pubmed-article:2655719 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:2655719 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:2655719 | pubmed:publicationType | Randomized Controlled Trial | lld:pubmed |
| pubmed-article:2655719 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2655719 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2655719 | lld:pubmed |
