| pubmed-article:2651407 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2651407 | lifeskim:mentions | umls-concept:C0014834 | lld:lifeskim |
| pubmed-article:2651407 | lifeskim:mentions | umls-concept:C0002563 | lld:lifeskim |
| pubmed-article:2651407 | lifeskim:mentions | umls-concept:C0220781 | lld:lifeskim |
| pubmed-article:2651407 | lifeskim:mentions | umls-concept:C1883254 | lld:lifeskim |
| pubmed-article:2651407 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:2651407 | pubmed:dateCreated | 1989-6-7 | lld:pubmed |
| pubmed-article:2651407 | pubmed:abstractText | A hemA mutant of Escherichia coli containing a multicopy plasmid which complemented the mutation excreted 5-aminolevulinic acid (ALA) into the medium. [1-14C]glutamate was substantially incorporated into ALA by this strain, whereas [2-14C]glycine was not. Periodate degradation of labeled ALA showed that C-5 of ALA was derived from C-1 of glutamate. The synthesis of ALA by two sonicate fractions which had been processed by gel filtration and dialysis, respectively, was dependent on glutamate, ATP, NADPH, tRNA(Glu), and pyridoxal phosphate. tRNA(Glu) stimulated ALA synthesis in a concentration-dependent manner. Pretreatment with RNase reduced this stimulation. The amino acid sequence of the cloned insert, derived from the nucleotide sequence (J.-M. Li, C. S. Russell, and S. D. Cosloy, J. Cell Biol. 107:617a, 1988), showed no homology with any ALA synthase sequenced to date. These results suggest that E. coli synthesizes ALA by the C5 pathway from the intact five-carbon chain of glutamate. | lld:pubmed |
| pubmed-article:2651407 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651407 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651407 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2651407 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651407 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2651407 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651407 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651407 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651407 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651407 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651407 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651407 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2651407 | pubmed:month | May | lld:pubmed |
| pubmed-article:2651407 | pubmed:issn | 0021-9193 | lld:pubmed |
| pubmed-article:2651407 | pubmed:author | pubmed-author:EisEE | lld:pubmed |
| pubmed-article:2651407 | pubmed:author | pubmed-author:CosloyS DSD | lld:pubmed |
| pubmed-article:2651407 | pubmed:author | pubmed-author:RussellC SCS | lld:pubmed |
| pubmed-article:2651407 | pubmed:author | pubmed-author:BrathwaiteOO | lld:pubmed |
| pubmed-article:2651407 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2651407 | pubmed:volume | 171 | lld:pubmed |
| pubmed-article:2651407 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2651407 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2651407 | pubmed:pagination | 2547-52 | lld:pubmed |
| pubmed-article:2651407 | pubmed:dateRevised | 2010-9-9 | lld:pubmed |
| pubmed-article:2651407 | pubmed:meshHeading | pubmed-meshheading:2651407-... | lld:pubmed |
| pubmed-article:2651407 | pubmed:meshHeading | pubmed-meshheading:2651407-... | lld:pubmed |
| pubmed-article:2651407 | pubmed:meshHeading | pubmed-meshheading:2651407-... | lld:pubmed |
| pubmed-article:2651407 | pubmed:meshHeading | pubmed-meshheading:2651407-... | lld:pubmed |
| pubmed-article:2651407 | pubmed:meshHeading | pubmed-meshheading:2651407-... | lld:pubmed |
| pubmed-article:2651407 | pubmed:meshHeading | pubmed-meshheading:2651407-... | lld:pubmed |
| pubmed-article:2651407 | pubmed:meshHeading | pubmed-meshheading:2651407-... | lld:pubmed |
| pubmed-article:2651407 | pubmed:year | 1989 | lld:pubmed |
| pubmed-article:2651407 | pubmed:articleTitle | 5-Aminolevulinic acid synthesis in Escherichia coli. | lld:pubmed |
| pubmed-article:2651407 | pubmed:affiliation | Department of Biochemistry, City College, City University of New York, New York 10031. | lld:pubmed |
| pubmed-article:2651407 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2651407 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:2651407 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2651407 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2651407 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2651407 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2651407 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2651407 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2651407 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2651407 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2651407 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2651407 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2651407 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2651407 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2651407 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2651407 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2651407 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2651407 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2651407 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2651407 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2651407 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2651407 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2651407 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2651407 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2651407 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2651407 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2651407 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2651407 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2651407 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2651407 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2651407 | lld:pubmed |
